GPAM1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GPAM1_HUMAN
• UniProt AC: Q8IXQ4
• Protein Name: GPALPP motifs-containing protein 1
• Gene Name: GPALPP1
• Organism: Homo sapiens (Human).
• Sequence Length: 340
• Protein Sequence: MARDLIGPALPPGFKARGTAEDEERDPSPVAGPALPPNYKSSSSDSSDSDEDSSSLYEEGNQESEEDDSGPTARKQRKNQDDDDDDDDGFFGPALPPGFKKQDDSPPRPIIGPALPPGFIKSTQKSDKGRDDPGQQETDSSEDEDIIGPMPAKGPVNYNVTTEFEKRAQRMKEKLTKGDDDSSKPIVRESWMTELPPEMKDFGLGPRTFKRRADDTSGDRSIWTDTPADRERKAKETQEARKSSSKKDEEHILSGRDKRLAEQVSSYNESKRSESLMDIHHKKLKSKAAEDKNKPQERIPFDRDKDLKVNRFDEAQKKALIKKSRELNTRFSHGKGNMFL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MARDLIGPA ------CCCCCCCCC		19413330
15	Acetylation	PALPPGFKARGTAED CCCCCCCCCCCCCCC		25953088
19	Phosphorylation	PGFKARGTAEDEERD CCCCCCCCCCCCCCC		23312004
28	Phosphorylation	EDEERDPSPVAGPAL CCCCCCCCCCCCCCC		25849741
72	Phosphorylation	EEDDSGPTARKQRKN CCCCCCHHHHHHHHC		-
105	Phosphorylation	GFKKQDDSPPRPIIG CCCCCCCCCCCCCCC		29255136
122	Phosphorylation	LPPGFIKSTQKSDKG CCCCCCCCCCCCCCC		21712546
123	Phosphorylation	PPGFIKSTQKSDKGR CCCCCCCCCCCCCCC		21712546
126	Phosphorylation	FIKSTQKSDKGRDDP CCCCCCCCCCCCCCC		28111955
138	Phosphorylation	DDPGQQETDSSEDED CCCCCCCCCCCCCCC		23927012
140	Phosphorylation	PGQQETDSSEDEDII CCCCCCCCCCCCCCC		23927012
141	Phosphorylation	GQQETDSSEDEDIIG CCCCCCCCCCCCCCC		23927012
158	Phosphorylation	PAKGPVNYNVTTEFE CCCCCCCCCCCHHHH		27642862
161	Phosphorylation	GPVNYNVTTEFEKRA CCCCCCCCHHHHHHH		28555341
184	Sumoylation	KGDDDSSKPIVRESW CCCCCCCCCCCCHHH		-
184	Sumoylation	KGDDDSSKPIVRESW CCCCCCCCCCCCHHH		-
207	Methylation	KDFGLGPRTFKRRAD HHCCCCCCCCCHHCC		115482397
216	Phosphorylation	FKRRADDTSGDRSIW CCHHCCCCCCCCCCC		22210691
220	Methylation	ADDTSGDRSIWTDTP CCCCCCCCCCCCCCH		115482389
226	Phosphorylation	DRSIWTDTPADRERK CCCCCCCCHHHHHHH		28555341
230	Methylation	WTDTPADRERKAKET CCCCHHHHHHHHHHH		115482405
243	Phosphorylation	ETQEARKSSSKKDEE HHHHHHHHCCHHHHH		29214152
244	Phosphorylation	TQEARKSSSKKDEEH HHHHHHHCCHHHHHH		29214152
245	Phosphorylation	QEARKSSSKKDEEHI HHHHHHCCHHHHHHH		29214152
247	Acetylation	ARKSSSKKDEEHILS HHHHCCHHHHHHHHC		30590185
254	Phosphorylation	KDEEHILSGRDKRLA HHHHHHHCHHHHHHH		24719451
265	Phosphorylation	KRLAEQVSSYNESKR HHHHHHHHHCCHHHH		26074081
266	Phosphorylation	RLAEQVSSYNESKRS HHHHHHHHCCHHHHC		26074081
267	Phosphorylation	LAEQVSSYNESKRSE HHHHHHHCCHHHHCH		26074081
270	Phosphorylation	QVSSYNESKRSESLM HHHHCCHHHHCHHHH		26074081
271	Sumoylation	VSSYNESKRSESLMD HHHCCHHHHCHHHHH		28112733
273	Phosphorylation	SYNESKRSESLMDIH HCCHHHHCHHHHHHH		26074081
275	Phosphorylation	NESKRSESLMDIHHK CHHHHCHHHHHHHHH		26074081
286	Phosphorylation	IHHKKLKSKAAEDKN HHHHHHHHHHHHHCC		26074081
308	Sumoylation	FDRDKDLKVNRFDEA CCCCCCCCCCCCCHH		28112733
308	Sumoylation	FDRDKDLKVNRFDEA CCCCCCCCCCCCCHH		-
329	Phosphorylation	KKSRELNTRFSHGKG HHHHHHHHHCCCCCC		24719451
330	Methylation	KSRELNTRFSHGKGN HHHHHHHHCCCCCCC		115482413
332	Phosphorylation	RELNTRFSHGKGNMF HHHHHHCCCCCCCCC		25159151
335	Methylation	NTRFSHGKGNMFL-- HHHCCCCCCCCCC--		72622741

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GPAM1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GPAM1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GPAM1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of GPAM1_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.