GPA1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GPA1_SCHPO
• UniProt AC: P27584
• Protein Name: Guanine nucleotide-binding protein alpha-1 subunit
• Gene Name: gpa1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 407
• Protein Description: Implicated in the mating and sporulation pathway. Probably coupled to mating-factor receptors. May act in concert with Ras1..
• Protein Sequence: MGCMSSKYADTSGGEVIQKKLSDTQTSNSSTTGSQNARVPVLENWLNIVLRGKPQNVESSGVRVKGNSTSGGNDIKVLLLGAGDSGKTTIMKQMRLLYSPGFSQVVRKQYRVMIFENIISSLCLLLEAMDNSNVSLLPENEKYRAVILRKHTSQPNEPFSPEIYEAVHALTLDTKLRTVQSCGTNLSLLDNFYYYQDHIDRIFDPQYIPSDQDILHCRIKTTGISEETFLLNRHHYRFFDVGGQRSERRKWIHCFENVTALLFLVSLAGYDQCLVEDNSGNQMQEALLLWDSICNSSWFSESAMILFLNKLDLFKRKVHISPIQKHFPDYQEVGSTPTFVQTQCPLADNAVRSGMYYFYLKFESLNRIASRSCYCHFTTATDTSLLQRVMVSVQDTIMSNNLQSLMF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Myristoylation	------MGCMSSKYA ------CCCCCCCCC	18.81	-
3	S-palmitoylation	-----MGCMSSKYAD -----CCCCCCCCCC	2.00	-
32	Phosphorylation	QTSNSSTTGSQNARV CCCCCCCCCCCCCCC	36.46	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GPA1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GPA1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GPA1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YIPC_SCHPO	SPAC343.04c	physical	16884933
BYR2_SCHPO	byr2	genetic	9315645

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.