dbPTM

GP1BB_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GP1BB_RAT
UniProt AC	Q9JJM7
Protein Name	Platelet glycoprotein Ib beta chain
Gene Name	Gp1bb
Organism	Rattus norvegicus (Rat).
Sequence Length	206
Subcellular Localization	Membrane Single-pass type I membrane protein .
Protein Description	Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium..
Protein Sequence	MGSRPRGALSLLLLLLAPPSRPASGCPAPCRCSETRVDCGRRGLTWASLPAAFPPDTTELVLTDNNLTALPPGLLDTLPALRRVHLGANPWRCDCRLLPLRAWLAGRPEREFYRDLRCVAPLALRGRLLPYVAEDELRAACAPGLLCWGALVAQLALLVLGLLHALLLALLLSRLRRLRAQARARSTREFSLTAPLVAESAGGGAS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
186	Phosphorylation	RAQARARSTREFSLT HHHHHHHCCCEEEEC	30.72	23984901
187	Phosphorylation	AQARARSTREFSLTA HHHHHHCCCEEEECH	28.76	23984901
191	Phosphorylation	ARSTREFSLTAPLVA HHCCCEEEECHHEEE	21.76	22673903
193	Phosphorylation	STREFSLTAPLVAES CCCEEEECHHEEEHH	25.65	23984901
200	Phosphorylation	TAPLVAESAGGGAS- CHHEEEHHCCCCCC-	23.60	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
191	S	Phosphorylation	Kinase	PKA	-	Uniprot

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GP1BB_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GP1BB_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of GP1BB_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GP1BB_RAT

Related Literatures of Post-Translational Modification