GP142_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GP142_HUMAN
• UniProt AC: Q7Z601
• Protein Name: Probable G-protein coupled receptor 142
• Gene Name: GPR142
• Organism: Homo sapiens (Human).
• Sequence Length: 462
• Subcellular Localization: Cell membrane; Multi-pass membrane protein.
• Protein Description: Orphan receptor..
• Protein Sequence: MSIMMLPMEQKIQWVPTSLQDITAVLGTEAYTEEDKSMVSHAQKSQHSCLSHSRWLRSPQVTGGSWDLRIRPSKDSSSFRQAQCLRKDPGANNHLESQGVRGTAGDADRELRGPSEKATAGQPRVTLLPTPHVSGLSQEFESHWPEIAERSPCVAGVIPVIYYSVLLGLGLPVSLLTAVALARLATRTRRPSYYYLLALTASDIIIQVVIVFAGFLLQGAVLARQVPQAVVRTANILEFAANHASVWIAILLTVDRYTALCHPLHHRAASSPGRTRRAIAAVLSAALLTGIPFYWWLDMWRDTDSPRTLDEVLKWAHCLTVYFIPCGVFLVTNSAIIHRLRRRGRSGLQPRVGKSTAILLGITTLFTLLWAPRVFVMLYHMYVAPVHRDWRVHLALDVANMVAMLHTAANFGLYCFVSKTFRATVRQVIHDAYLPCTLASQPEGMAAKPVMEPPGLPTGAEV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSIMMLPME ------CCCCCCCHH	21.13	29759185
37	Phosphorylation	AYTEEDKSMVSHAQK CCCHHHHHHHHHHHH	36.42	23403867
40	Phosphorylation	EEDKSMVSHAQKSQH HHHHHHHHHHHHHHH	12.40	23403867
130	Phosphorylation	PRVTLLPTPHVSGLS CCEEEECCCCCCCCC	26.46	26853621
289	Phosphorylation	VLSAALLTGIPFYWW HHHHHHHHCCCCHHH	33.64	22210691
294	Phosphorylation	LLTGIPFYWWLDMWR HHHCCCCHHHHHHCC	7.13	22210691
346	Phosphorylation	RLRRRGRSGLQPRVG HHHHCCCCCCCCCCC	46.83	23312004
407	Phosphorylation	NMVAMLHTAANFGLY HHHHHHHHHHHCCCE	24.41	25002506
414	Phosphorylation	TAANFGLYCFVSKTF HHHHCCCEEECCHHH	5.57	25002506
418	Phosphorylation	FGLYCFVSKTFRATV CCCEEECCHHHHHHH	13.01	25002506
420	Phosphorylation	LYCFVSKTFRATVRQ CEEECCHHHHHHHHH	15.73	25002506
424	Phosphorylation	VSKTFRATVRQVIHD CCHHHHHHHHHHHHH	16.38	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GP142_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GP142_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GP142_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of GP142_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.