GP101_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GP101_HUMAN
• UniProt AC: Q96P66
• Protein Name: Probable G-protein coupled receptor 101
• Gene Name: GPR101
• Organism: Homo sapiens (Human).
• Sequence Length: 508
• Subcellular Localization: Cell membrane; Multi-pass membrane protein.
• Protein Description: Orphan receptor..
• Protein Sequence: MTSTCTNSTRESNSSHTCMPLSKMPISLAHGIIRSTVLVIFLAASFVGNIVLALVLQRKPQLLQVTNRFIFNLLVTDLLQISLVAPWVVATSVPLFWPLNSHFCTALVSLTHLFAFASVNTIVVVSVDRYLSIIHPLSYPSKMTQRRGYLLLYGTWIVAILQSTPPLYGWGQAAFDERNALCSMIWGASPSYTILSVVSFIVIPLIVMIACYSVVFCAARRQHALLYNVKRHSLEVRVKDCVENEDEEGAEKKEEFQDESEFRRQHEGEVKAKEGRMEAKDGSLKAKEGSTGTSESSVEARGSEEVRESSTVASDGSMEGKEGSTKVEENSMKADKGRTEVNQCSIDLGEDDMEFGEDDINFSEDDVEAVNIPESLPPSRRNSNSNPPLPRCYQCKAAKVIFIIIFSYVLSLGPYCFLAVLAVWVDVETQVPQWVITIIIWLFFLQCCIHPYVYGYMHKTIKKEIQDMLKKFFCKEKPPKEDSHPDLPGTEGGTEGKIVPSYDSATFP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTSTCTNST ------CCCCCCCCC	32.51	24043423
3	Phosphorylation	-----MTSTCTNSTR -----CCCCCCCCCC	21.86	24043423
4	Phosphorylation	----MTSTCTNSTRE ----CCCCCCCCCCC	17.74	24043423
6	Phosphorylation	--MTSTCTNSTRESN --CCCCCCCCCCCCC	32.09	24043423
7	N-linked_Glycosylation	-MTSTCTNSTRESNS -CCCCCCCCCCCCCC	43.46	UniProtKB CARBOHYD
8	Phosphorylation	MTSTCTNSTRESNSS CCCCCCCCCCCCCCC	15.64	24043423
9	Phosphorylation	TSTCTNSTRESNSSH CCCCCCCCCCCCCCC	40.29	24043423
13	N-linked_Glycosylation	TNSTRESNSSHTCMP CCCCCCCCCCCCCEE	42.66	UniProtKB CARBOHYD
15	Phosphorylation	STRESNSSHTCMPLS CCCCCCCCCCCEEHH	27.37	-
27	Phosphorylation	PLSKMPISLAHGIIR EHHHCCHHHHHHHHH	17.40	-
130	Phosphorylation	VVVSVDRYLSIIHPL EEEEECHHHHHHCCC	10.59	26074081
141	Phosphorylation	IHPLSYPSKMTQRRG HCCCCCCCCCCCCCC	27.16	26074081
144	Phosphorylation	LSYPSKMTQRRGYLL CCCCCCCCCCCCEEE	23.74	26074081
309	Phosphorylation	GSEEVRESSTVASDG CCHHHHHCCEECCCC	22.27	-
310	Phosphorylation	SEEVRESSTVASDGS CHHHHHCCEECCCCC	23.34	-
393	Phosphorylation	NPPLPRCYQCKAAKV CCCCCCHHHHHHHHH	20.44	28796482

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GP101_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GP101_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
130	Phosphorylation	124 (6)	V ⇒ L	rs1190736	Body mass index	28892062

Protein-Protein Interaction

Oops, there are no PPI records of GP101_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.