dbPTM

GON4L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GON4L_HUMAN
UniProt AC	Q3T8J9
Protein Name	GON-4-like protein
Gene Name	GON4L
Organism	Homo sapiens (Human).
Sequence Length	2241
Subcellular Localization	Nucleus .
Protein Description	Has transcriptional repressor activity, probably as part of a complex with YY1, SIN3A AND HDAC1. Required for B cell lymphopoiesis..
Protein Sequence	MLPCKKRRTTVTESLQHKGNQEENNVDLESAVKPESDQVKDLSSVSLSWDPSHGRVAGFEVQSLQDAGNQLGMEDTSLSSGMLTQNTNVPILEGVDVAISQGITLPSLESFHPLNIHIGKGKLHATGSKRGKKMTLRPGPVTQEDRCDHLTLKEPFSGEPSEEVKEEGGKPQMNSEGEIPSLPSGSQSAKPVSQPRKSTQPDVCASPQEKPLRTLFHQPEEEIEDGGLFIPMEEQDNEESEKRRKKKKGTKRKRDGRGQEGTLAYDLKLDDMLDRTLEDGAKQHNLTAVNVRNILHEVITNEHVVAMMKAAISETEDMPMFEPKMTRSKLKEVVEKGVVIPTWNISPIKKANEIKPPQFVDIHLEEDDSSDEEYQPDDEEEDETAEESLLESDVESTASSPRGAKKSRLRQSSEMTETDEESGILSEAEKVTTPAIRHISAEVVPMGPPPPPKPKQTRDSTFMEKLHAVDEELASSPVCMDSFQPMDDSLIAFRTRSKMPLKDVPLGQLEAELQAPDITPDMYDPNTADDEDWKMWLGGLMNDDVGNEDEADDDDDPEYNFLEDLDEPDTEDFRTDRAVRITKKEVNELMEELFETFQDEMGFSNMEDDGPEEEECVAEPRPNFNTPQALRFEEPLANLLNEQHRTVKELFEQLKMKKSSAKQLQEVEKVKPQSEKVHQTLILDPAQRKRLQQQMQQHVQLLTQIHLLATCNPNLNPEATTTRIFLKELGTFAQSSIALHHQYNPKFQTLFQPCNLMGAMQLIEDFSTHVSIDCSPHKTVKKTANEFPCLPKQVAWILATSKVFMYPELLPVCSLKAKNPQDKIVFTKAEDNLLALGLKHFEGTEFPNPLISKYLLTCKTAHQLTVRIKNLNMNRAPDNIIKFYKKTKQLPVLGKCCEEIQPHQWKPPIEREEHRLPFWLKASLPSIQEELRHMADGAREVGNMTGTTEINSDRSLEKDNLELGSESRYPLLLPKGVVLKLKPVATRFPRKAWRQKRSSVLKPLLIQPSPSLQPSFNPGKTPARSTHSEAPPSKMVLRIPHPIQPATVLQTVPGVPPLGVSGGESFESPAALPAVPPEARTSFPLSESQTLLSSAPVPKVMLPSLAPSKFRKPYVRRRPSKRRGVKASPCMKPAPVIHHPASVIFTVPATTVKIVSLGGGCNMIQPVNAAVAQSPQTIPITTLLVNPTSFPCPLNQSLVASSVSPLIVSGNSVNLPIPSTPEDKAHVNVDIACAVADGENAFQGLEPKLEPQELSPLSATVFPKVEHSPGPPLADAECQEGLSENSACRWTVVKTEEGRQALEPLPQGIQESLNNPTPGDLEEIVKMEPEEAREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQKEEERSQPTKTPSSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPPGKPEDSSSVDGQSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQETMEKLTWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAVGDSAEKPPTFASPETAPEVETSRTPPGESIKAAGKGRNNHRARNKRGSRARASKDTSKLLLLYDEDILERDPLREQKDLAFAQAYLTRVREALQHIPGKYEDFLQVIYEFESSTQRRTAVDLYKSLQILLQDWPQLLKDFAAFLLPEQALACGLFEEQQAFEKSRKFLRQLEICFAENPSHHQKIIKVLQGCADCLPQEITELKTQMWQLLKGHDHLQDEFSIFFDHLRPAASRMGDFEEINWTEEKEYEFDGFEEVALPDVEEEEEPPKIPTASKNKRKKEIGVQNHDKETEWPDGAKDCACSCHEGGPDSKLKKSKRRSCSHCSSKVCDSKSYKSKEPHELVGSSPHREASPMPGAKEAGQGKDMMEEEAPEERESTEATQSRTVRTTRKGEMPVSAGLAVGSTLPSPREVTVTERLLLDGPPPHSPETPQFPPTTGAVLYTVKRNQVGPEVRSCPKASPRLQKEREGQKAVSESEALMLVWDASETEKLPGTVEPPASFLSPVSSKTRDAGRRHVSGKPDTQERWLPSSRARVKTRDRTCPVHESPSGIDTSETSPKAPRGGLAKDSGTQAKGPEGEQQPKAAEATVCANNSKVSSTGEKVVLWTREADRVILTMCQEQGAQPQTFNIISQQLGNKTPAEVSHRFRELMQLFHTACEASSEDEDDATSTSNADQLSDHGDLLSEEELDE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	LPCKKRRTTVTESLQ CCCCCCCCCHHHHHH	29.65	23312004
10	Phosphorylation	PCKKRRTTVTESLQH CCCCCCCCHHHHHHC	24.50	29116813
12	Phosphorylation	KKRRTTVTESLQHKG CCCCCCHHHHHHCCC	20.12	29116813
14	Phosphorylation	RRTTVTESLQHKGNQ CCCCHHHHHHCCCCC	24.78	29116813
46	Phosphorylation	VKDLSSVSLSWDPSH CCCHHCCEEEECCCC	20.73	28555341
52	Phosphorylation	VSLSWDPSHGRVAGF CEEEECCCCCCCCCE	35.78	27050516
126	Phosphorylation	GKGKLHATGSKRGKK CCCCCCCCCCCCCCE	31.10	24719451
157	Phosphorylation	LTLKEPFSGEPSEEV EEECCCCCCCCCHHH	53.62	30206219
161	Phosphorylation	EPFSGEPSEEVKEEG CCCCCCCCHHHHHCC	41.93	30206219
181	Phosphorylation	NSEGEIPSLPSGSQS CCCCCCCCCCCCCCC	59.58	22817900
188	Phosphorylation	SLPSGSQSAKPVSQP CCCCCCCCCCCCCCC	39.70	22817900
198	Phosphorylation	PVSQPRKSTQPDVCA CCCCCCCCCCCCCCC	33.29	26552605
199	Phosphorylation	VSQPRKSTQPDVCAS CCCCCCCCCCCCCCC	47.35	26552605
206	Phosphorylation	TQPDVCASPQEKPLR CCCCCCCCCCCCCHH	23.22	30266825
276	Phosphorylation	LDDMLDRTLEDGAKQ HHHHHHHHHHHHHHH	33.88	22199227
282	Ubiquitination	RTLEDGAKQHNLTAV HHHHHHHHHCCCEEE	58.58	-
300	Phosphorylation	NILHEVITNEHVVAM HHHHHHHCCHHHHHH	39.47	29038488
309	Acetylation	EHVVAMMKAAISETE HHHHHHHHHHHHCCC	22.91	18530553
331	Ubiquitination	KMTRSKLKEVVEKGV CCCHHHHHHHHHCCC	52.80	-
342	Phosphorylation	EKGVVIPTWNISPIK HCCCEECCCCCCCCC	21.73	23927012
346	Phosphorylation	VIPTWNISPIKKANE EECCCCCCCCCCCCC	19.84	25159151
413	Phosphorylation	KSRLRQSSEMTETDE HHHHHCCCCCCCCHH	24.05	-
416	Phosphorylation	LRQSSEMTETDEESG HHCCCCCCCCHHHCC	31.51	28985074
418	Phosphorylation	QSSEMTETDEESGIL CCCCCCCCHHHCCCC	39.27	30576142
426	Phosphorylation	DEESGILSEAEKVTT HHHCCCCCHHHHCCC	32.60	-
475	Phosphorylation	AVDEELASSPVCMDS HHCHHHHCCCCCHHC	48.04	27732954
476	Phosphorylation	VDEELASSPVCMDSF HCHHHHCCCCCHHCC	18.75	25849741
482	Phosphorylation	SSPVCMDSFQPMDDS CCCCCHHCCCCCCCC	10.01	27732954
489	Phosphorylation	SFQPMDDSLIAFRTR CCCCCCCCEEEEEEC	19.87	27080861
527	Phosphorylation	PDMYDPNTADDEDWK CCCCCCCCCCHHHHH	36.53	26657352
534	Ubiquitination	TADDEDWKMWLGGLM CCCHHHHHHHHHHHH	32.30	17370265
626	Phosphorylation	EPRPNFNTPQALRFE CCCCCCCCCHHHCCH	16.79	25159151
655	Ubiquitination	KELFEQLKMKKSSAK HHHHHHHHCHHHHHH	48.66	-
659	Phosphorylation	EQLKMKKSSAKQLQE HHHHCHHHHHHHHHH	29.97	26074081
660	Phosphorylation	QLKMKKSSAKQLQEV HHHCHHHHHHHHHHH	48.65	26074081
662	Ubiquitination	KMKKSSAKQLQEVEK HCHHHHHHHHHHHHC	54.19	-
775	Phosphorylation	THVSIDCSPHKTVKK CCEEEECCCCCCCCC	26.70	25627689
782	Ubiquitination	SPHKTVKKTANEFPC CCCCCCCCCCCCCCC	48.83	-
816	Ubiquitination	LLPVCSLKAKNPQDK HHHHHCCCCCCCCCC	40.81	-
818	Ubiquitination	PVCSLKAKNPQDKIV HHHCCCCCCCCCCEE	68.52	-
823	Ubiquitination	KAKNPQDKIVFTKAE CCCCCCCCEEEEECH	35.21	-
828	Ubiquitination	QDKIVFTKAEDNLLA CCCEEEEECHHCHHH	38.01	-
839	Ubiquitination	NLLALGLKHFEGTEF CHHHHCCCCCCCCCC	44.44	-
860	Phosphorylation	KYLLTCKTAHQLTVR HHHHHCCCHHHEEEE	31.36	28555341
865	Phosphorylation	CKTAHQLTVRIKNLN CCCHHHEEEEEECCC	10.94	24719451
869	Ubiquitination	HQLTVRIKNLNMNRA HHEEEEEECCCCCCC	44.83	21890473
882	Ubiquitination	RAPDNIIKFYKKTKQ CCCCCHHHHHHHHCC	38.55	-
888	Ubiquitination	IKFYKKTKQLPVLGK HHHHHHHCCCCCCHH	59.73	-
895	Ubiquitination	KQLPVLGKCCEEIQP CCCCCCHHHCCCCCC	31.39	-
921	Ubiquitination	HRLPFWLKASLPSIQ CCCCHHHHCCCHHHH	26.90	-
944	Sulfoxidation	GAREVGNMTGTTEIN HHHHCCCCCCCCEEC	2.77	21406390
955	Phosphorylation	TEINSDRSLEKDNLE CEECCCCCCCCCCCC	45.96	28555341
958	Ubiquitination	NSDRSLEKDNLELGS CCCCCCCCCCCCCCC	58.15	-
965	Phosphorylation	KDNLELGSESRYPLL CCCCCCCCCCCCCEE	45.05	20873877
967	Phosphorylation	NLELGSESRYPLLLP CCCCCCCCCCCEEEC	38.52	20873877
969	Phosphorylation	ELGSESRYPLLLPKG CCCCCCCCCEEECCC	13.91	20873877
975	Ubiquitination	RYPLLLPKGVVLKLK CCCEEECCCEEEEEE	65.39	-
998	Phosphorylation	KAWRQKRSSVLKPLL HHHHHHHHHCCHHHC	35.56	27080861
999	Phosphorylation	AWRQKRSSVLKPLLI HHHHHHHHCCHHHCC	35.19	27080861
1002	Sumoylation	QKRSSVLKPLLIQPS HHHHHCCHHHCCCCC	31.31	-
1002	Acetylation	QKRSSVLKPLLIQPS HHHHHCCHHHCCCCC	31.31	26051181
1002	Sumoylation	QKRSSVLKPLLIQPS HHHHHCCHHHCCCCC	31.31	-
1002	Ubiquitination	QKRSSVLKPLLIQPS HHHHHCCHHHCCCCC	31.31	-
1009	Phosphorylation	KPLLIQPSPSLQPSF HHHCCCCCCCCCCCC	15.67	25159151
1011	Phosphorylation	LLIQPSPSLQPSFNP HCCCCCCCCCCCCCC	43.93	25627689
1020	Acetylation	QPSFNPGKTPARSTH CCCCCCCCCCCCCCC	53.22	25953088
1047	Phosphorylation	PHPIQPATVLQTVPG CCCCCCCEEEEECCC	28.56	20068231
1082	Phosphorylation	VPPEARTSFPLSESQ CCCCHHCCCCCCHHH	21.22	28555341
1086	Phosphorylation	ARTSFPLSESQTLLS HHCCCCCCHHHHHHH	35.13	23186163
1088	Phosphorylation	TSFPLSESQTLLSSA CCCCCCHHHHHHHCC	25.70	23917254
1090	Phosphorylation	FPLSESQTLLSSAPV CCCCHHHHHHHCCCC	38.66	24719451
1093	Phosphorylation	SESQTLLSSAPVPKV CHHHHHHHCCCCCCC	27.80	24425749
1109	Acetylation	LPSLAPSKFRKPYVR CCCCCCHHCCCCCCC	48.40	25953088
1126	Methylation	PSKRRGVKASPCMKP CCCCCCCCCCCCCCC	46.07	23748837
1132	Acetylation	VKASPCMKPAPVIHH CCCCCCCCCCCCCCC	44.75	26051181
1156	Phosphorylation	ATTVKIVSLGGGCNM CCEEEEEEECCCCCC	25.44	20068231
1197	O-linked_Glycosylation	FPCPLNQSLVASSVS CCCCCCHHHHHCCCC	24.60	30379171
1209	Phosphorylation	SVSPLIVSGNSVNLP CCCCEEEECCCEECC	25.84	19664995
1248	Sumoylation	AFQGLEPKLEPQELS CCCCCCCCCCHHHCC	56.99	-
1255	Phosphorylation	KLEPQELSPLSATVF CCCHHHCCCCEEEEE	24.04	29255136
1258	Phosphorylation	PQELSPLSATVFPKV HHHCCCCEEEEECCC	25.85	30266825
1260	Phosphorylation	ELSPLSATVFPKVEH HCCCCEEEEECCCCC	21.21	23927012
1264	Sumoylation	LSATVFPKVEHSPGP CEEEEECCCCCCCCC	49.11	-
1268	Phosphorylation	VFPKVEHSPGPPLAD EECCCCCCCCCCCCC	20.32	23401153
1283	Phosphorylation	AECQEGLSENSACRW HHHHHCCCCCCCCCE	45.66	23927012
1286	Phosphorylation	QEGLSENSACRWTVV HHCCCCCCCCCEEEE	25.37	23927012
1294	Sumoylation	ACRWTVVKTEEGRQA CCCEEEEECHHHHHH	45.97	-
1294	Sumoylation	ACRWTVVKTEEGRQA CCCEEEEECHHHHHH	45.97	-
1294	Ubiquitination	ACRWTVVKTEEGRQA CCCEEEEECHHHHHH	45.97	-
1337	Phosphorylation	EEAREEISGSPERDI HHHHHHHCCCCCCCC	36.18	30266825
1339	Phosphorylation	AREEISGSPERDICD HHHHHCCCCCCCCCC	19.45	30266825
1391	Phosphorylation	SQPTKTPSSSQEPPD CCCCCCCCCCCCCCC	48.10	30576142
1393	Phosphorylation	PTKTPSSSQEPPDEG CCCCCCCCCCCCCCC	42.79	30576142
1401	Phosphorylation	QEPPDEGTSGTDVNK CCCCCCCCCCCCCCC	23.18	30576142
1402	Phosphorylation	EPPDEGTSGTDVNKG CCCCCCCCCCCCCCC	51.02	28985074
1408	Acetylation	TSGTDVNKGSSKNAL CCCCCCCCCCCCCCH	61.08	26051181
1416	Phosphorylation	GSSKNALSSMDPEVR CCCCCCHHHCCCCCC	22.62	29214152
1417	Phosphorylation	SSKNALSSMDPEVRL CCCCCHHHCCCCCCC	28.23	29214152
1425	Phosphorylation	MDPEVRLSSPPGKPE CCCCCCCCCCCCCCC	30.18	25159151
1426	Phosphorylation	DPEVRLSSPPGKPED CCCCCCCCCCCCCCC	39.44	25159151
1434	Phosphorylation	PPGKPEDSSSVDGQS CCCCCCCCCCCCCCC	23.89	29255136
1435	Phosphorylation	PGKPEDSSSVDGQSV CCCCCCCCCCCCCCC	46.86	29255136
1436	Phosphorylation	GKPEDSSSVDGQSVG CCCCCCCCCCCCCCC	28.34	29255136
1441	Phosphorylation	SSSVDGQSVGTPVGP CCCCCCCCCCCCCCC	28.22	29255136
1444	Phosphorylation	VDGQSVGTPVGPETG CCCCCCCCCCCCCCC	16.79	29255136
1450	Phosphorylation	GTPVGPETGGEKNGP CCCCCCCCCCCCCCC	54.33	29255136
1502	Phosphorylation	EKLTWLASERRMSQE HHHHHHHHHHHHHHC	29.48	24719451
1552	Phosphorylation	TDEAVGDSAEKPPTF CHHHCCCCCCCCCCC	32.19	30177828
1570	Phosphorylation	ETAPEVETSRTPPGE CCCCCCCCCCCCCCH	28.78	25627689
1571	Phosphorylation	TAPEVETSRTPPGES CCCCCCCCCCCCCHH	22.20	25627689
1573	Phosphorylation	PEVETSRTPPGESIK CCCCCCCCCCCHHHH	33.33	25627689
1750	Phosphorylation	DCLPQEITELKTQMW HHCCHHHHHHHHHHH	34.22	23403867
1754	Phosphorylation	QEITELKTQMWQLLK HHHHHHHHHHHHHHC	35.96	20068231
1853	Phosphorylation	GAKDCACSCHEGGPD CCCCCCCCCCCCCCC	10.45	25159151
1870	Phosphorylation	LKKSKRRSCSHCSSK HCHHCCCCCCCCCCC	24.81	26552605
1872	Phosphorylation	KSKRRSCSHCSSKVC HHCCCCCCCCCCCCC	28.86	26552605
1875	Phosphorylation	RRSCSHCSSKVCDSK CCCCCCCCCCCCCCC	27.98	26552605
1876	Phosphorylation	RSCSHCSSKVCDSKS CCCCCCCCCCCCCCC	34.21	26552605
1881	Phosphorylation	CSSKVCDSKSYKSKE CCCCCCCCCCCCCCC	20.55	26552605
1883	Phosphorylation	SKVCDSKSYKSKEPH CCCCCCCCCCCCCCH	41.57	26552605
1884	Phosphorylation	KVCDSKSYKSKEPHE CCCCCCCCCCCCCHH	24.02	26552605
1886	Phosphorylation	CDSKSYKSKEPHELV CCCCCCCCCCCHHHC	33.74	28176443
1887	Acetylation	DSKSYKSKEPHELVG CCCCCCCCCCHHHCC	71.73	12429985
1895	Phosphorylation	EPHELVGSSPHREAS CCHHHCCCCCCCCCC	32.96	30266825
1896	Phosphorylation	PHELVGSSPHREASP CHHHCCCCCCCCCCC	20.85	30266825
1902	Phosphorylation	SSPHREASPMPGAKE CCCCCCCCCCCCCHH	19.58	30266825
1914	Acetylation	AKEAGQGKDMMEEEA CHHCCCCCCCCCCCC	34.26	26051181
1927	Phosphorylation	EAPEERESTEATQSR CCCHHHHCCHHHHCC	37.46	24719451
1928	Phosphorylation	APEERESTEATQSRT CCHHHHCCHHHHCCE	25.53	30576142
1935	Phosphorylation	TEATQSRTVRTTRKG CHHHHCCEECCCCCC	21.42	30576142
1947 (in isoform 3)	Phosphorylation	-	15.68	20068231
1953 (in isoform 3)	Phosphorylation	-	14.87	30266825
1954 (in isoform 3)	Phosphorylation	-	21.85	30266825
1957 (in isoform 3)	Phosphorylation	-	42.23	30266825
1958	Phosphorylation	AVGSTLPSPREVTVT ECCCCCCCCCEEEEE	39.44	20068231
1977	Phosphorylation	LDGPPPHSPETPQFP CCCCCCCCCCCCCCC	30.15	25159151
1980	Phosphorylation	PPPHSPETPQFPPTT CCCCCCCCCCCCCCC	26.27	28450419
1986	Phosphorylation	ETPQFPPTTGAVLYT CCCCCCCCCCCEEEE	37.79	28450419
1987	Phosphorylation	TPQFPPTTGAVLYTV CCCCCCCCCCEEEEE	28.99	26074081
1992	Phosphorylation	PTTGAVLYTVKRNQV CCCCCEEEEEECCCC	11.68	-
2010	Phosphorylation	VRSCPKASPRLQKER HHCCCCCCHHHHHHH	19.38	24719451
2044	Phosphorylation	ETEKLPGTVEPPASF HCCCCCCCCCCCHHH	21.54	26074081
2050	Phosphorylation	GTVEPPASFLSPVSS CCCCCCHHHCCCCCC	32.28	29255136
2053	Phosphorylation	EPPASFLSPVSSKTR CCCHHHCCCCCCCCC	22.65	29255136
2056	Phosphorylation	ASFLSPVSSKTRDAG HHHCCCCCCCCCCCC	29.51	29255136
2057	Phosphorylation	SFLSPVSSKTRDAGR HHCCCCCCCCCCCCC	37.98	29255136
2059	Phosphorylation	LSPVSSKTRDAGRRH CCCCCCCCCCCCCCC	35.41	26074081
2070	Acetylation	GRRHVSGKPDTQERW CCCCCCCCCCCHHCC	32.01	23749302
2091	Phosphorylation	RVKTRDRTCPVHESP CCCCCCCCCCCCCCC	26.00	30576142
2097	Phosphorylation	RTCPVHESPSGIDTS CCCCCCCCCCCCCCC	14.97	28450419
2099	Phosphorylation	CPVHESPSGIDTSET CCCCCCCCCCCCCCC	58.63	28450419
2103	Phosphorylation	ESPSGIDTSETSPKA CCCCCCCCCCCCCCC	26.92	21712546
2104	Phosphorylation	SPSGIDTSETSPKAP CCCCCCCCCCCCCCC	34.82	23898821
2106	Phosphorylation	SGIDTSETSPKAPRG CCCCCCCCCCCCCCC	50.53	25159151
2107	Phosphorylation	GIDTSETSPKAPRGG CCCCCCCCCCCCCCC	21.98	10997877
2117	Acetylation	APRGGLAKDSGTQAK CCCCCCCCCCCCCCC	58.43	23749302
2119	Phosphorylation	RGGLAKDSGTQAKGP CCCCCCCCCCCCCCC	42.93	29759185
2121	Phosphorylation	GLAKDSGTQAKGPEG CCCCCCCCCCCCCCC	29.34	29759185
2144	Phosphorylation	ATVCANNSKVSSTGE EEEECCCCCCCCCCC	33.95	-
2147	Phosphorylation	CANNSKVSSTGEKVV ECCCCCCCCCCCEEE	26.39	-
2148	Phosphorylation	ANNSKVSSTGEKVVL CCCCCCCCCCCEEEE	43.34	-
2157	Phosphorylation	GEKVVLWTREADRVI CCEEEEEECCCCCEE	17.92	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GON4L_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GON4L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GON4L_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of GON4L_HUMAN !!

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GON4L_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1255 AND SER-1977, ANDMASS SPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-206; SER-1255 ANDSER-2053, AND MASS SPECTROMETRY.	19413330 [Abstract]
"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column."; Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.; Anal. Sci. 24:161-166(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-181 AND SER-188, ANDMASS SPECTROMETRY.	18187866 [Abstract]
Ubiquitylation
Reference	PubMed
"Tryptic digestion of ubiquitin standards reveals an improved strategyfor identifying ubiquitinated proteins by mass spectrometry."; Denis N.J., Vasilescu J., Lambert J.-P., Smith J.C., Figeys D.; Proteomics 7:868-874(2007). Cited for: UBIQUITINATION [LARGE SCALE ANALYSIS] AT LYS-534, AND MASSSPECTROMETRY.	17370265 [Abstract]