GOGA7_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GOGA7_RAT
• UniProt AC: Q6AYQ1
• Protein Name: Golgin subfamily A member 7
• Gene Name: Golga7
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 137
• Subcellular Localization: Golgi apparatus membrane; Lipid-anchor.
• Protein Description: May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS (By similarity)..
• Protein Sequence: MRPQQAPVSGKVFIQRDYSSGTRCQFQTKFPAELENRVDRQQFEETVRTLNNLYAEAEKLGGQSYLEGCLACLTAYTIFLCMETHYEKVLKKVSKYIQEQNEKIYAPQGLLLTDPIERGLRVIEITIYEDRGVSSGR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
69	S-palmitoylation	GQSYLEGCLACLTAY CCHHHHHHHHHHHHH	1.27	-
72	S-palmitoylation	YLEGCLACLTAYTIF HHHHHHHHHHHHHHH	1.93	-
95	Ubiquitination	KVLKKVSKYIQEQNE HHHHHHHHHHHHHHC	49.73	-
103	Ubiquitination	YIQEQNEKIYAPQGL HHHHHHCCCCCCCCE	48.87	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GOGA7_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
69	C	Palmitoylation	Palmitoylated on Cys-69 and Cys-72; which is required for Golgi localization and interaction with GOLGA3.	-
72	C	Palmitoylation	Palmitoylated on Cys-69 and Cys-72; which is required for Golgi localization and interaction with GOLGA3.	-

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GOGA7_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of GOGA7_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.