GOGA5_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GOGA5_DROME
• UniProt AC: Q8SZ63
• Protein Name: Golgin-84
• Gene Name: Golgin84
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 516
• Subcellular Localization: Golgi apparatus membrane; Single-pass type IV membrane protein.
• Protein Description: May be involved in maintaining Golgi structure and in intra-Golgi transport..
• Protein Sequence: MSSWITGLADKAENILNKLDQNAATALQTENATGSADPMRRSMTSSTQSLSTSLKSTLSPVRRSGANSSSSVKSDGGVSVVTKDMRQKMTTSASFSNSPDISANSMDTNELAAFKIALNEITAERDELRLRLEDLNNETEKFDLHQHTQVLEALVKSLSEERDKAVHDYNEAQAANMAYVHSISELETNLAKLQQEYISAAHKLQMQTKETEQQRQELQEYRIKAQRALQAKDSLIAELKAKPTEEGADPNLVSKDSETRFLQIEHESLKQELEHANEELQKARLQLDDYVSQERQRQVELSSARQREETLAKELRQAREHSVTSESDQRVLTQELASLRQQLSNQMAAAATRLQEREQQLQQMRQRLSEEANTGAKSDYETRLKALTQSLVERQSLLERVTSERNALRLQHEKAQTQLQQNMHLVEMESQRGSSRHTMLNSTDDVKAQFPLLMHPSPFDNRVARRFKRALRQADSMGIRVGTFLRRYPMMRVSVIVYVALLHLWVMFVLLSTTPN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
42	Phosphorylation	SADPMRRSMTSSTQS CCCHHHHHCCCCHHH	18.95	19429919
44	Phosphorylation	DPMRRSMTSSTQSLS CHHHHHCCCCHHHHC	22.29	19429919
45	Phosphorylation	PMRRSMTSSTQSLST HHHHHCCCCHHHHCH	23.81	19429919
46	Phosphorylation	MRRSMTSSTQSLSTS HHHHCCCCHHHHCHH	22.69	19429919
47	Phosphorylation	RRSMTSSTQSLSTSL HHHCCCCHHHHCHHH	23.19	19429919
64	Phosphorylation	TLSPVRRSGANSSSS HCCCCCCCCCCCCCC	31.52	22817900
71	Phosphorylation	SGANSSSSVKSDGGV CCCCCCCCCCCCCCE	35.20	22817900
74	Phosphorylation	NSSSSVKSDGGVSVV CCCCCCCCCCCEEEE	39.05	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GOGA5_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GOGA5_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GOGA5_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of Drosophila melanogaster embryos.";
Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.;
J. Proteome Res. 7:1675-1682(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-64 AND SER-74, AND MASSSPECTROMETRY.
PubMed: 18327897