GOGA1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GOGA1_MOUSE
• UniProt AC: Q9CW79
• Protein Name: Golgin subfamily A member 1
• Gene Name: Golga1
• Organism: Mus musculus (Mouse).
• Sequence Length: 758
• Subcellular Localization: Golgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein . Cytoplasmic vesicle, secretory vesicle, acrosome .
• Protein Description: Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking..
• Protein Sequence: MFAKLKKKIAEETAVAQRPGGTTRIPRSVSKESVASMGADSGDDFASDGSSSREDLSSQLLRRNEQIRKLEARLSDYAEQVRNLQKIKEKLEIALEKHQDSSMRKFQEQNETFQASRAKMAEGLALALARKDQEWSEKMEQLEKDKRFLTSQLQEVKNQSLSLFQKRDEIDELEGFQQQEISKVKHMLLKKEECLGKMEQELDARTRELNRTQEELVTSNQLSSDLNERLEELQRHCSTLEEQRDHLTASKAGAEHKIVVLEQKEQELQAIIQQHSIDLQKVTAETQEKEKVITHLQEKVIFLEKRLEQNLSGEDHVQELLKEKTVAEQNLEDTRQQLLAARNSHTKALYLLETRVKDLERSLQAAEEQLSQSRNVVADQEAQIQKLITTNQENSLSQQQVLALEQHCRERIHALEAQIEALEQTRVADQIASEQGMLQLQQENVALKESRNECEHSLQHHQLELKKLKDEWSQREIVSVAMAQALEEVRKQREEFQQQATELTAIIEEKNQSLCEKDEALLQKEQELRQLEKGHSSALLQMHKLQRELEALKTCKAQEAMPATTGEDCLPLQGQEPLVISKAMQNSEYELPAAEGTPNGEVGASDLKQLQKEKQDLEQQLIEKNKIMKQMQQRMLELKKTLQKELKIRPDSELFEVREKTGPEIPNMAPSVTNNTDLTDAREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENMLKETLEYKMSWFGSKPTPKGSIRPSISNPRIPWS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
22	Phosphorylation	VAQRPGGTTRIPRSV HCCCCCCCCCCCCCC	20.86	23375375
23	Phosphorylation	AQRPGGTTRIPRSVS CCCCCCCCCCCCCCC	29.85	23375375
28	Phosphorylation	GTTRIPRSVSKESVA CCCCCCCCCCHHHHH	25.95	26643407
30	Phosphorylation	TRIPRSVSKESVASM CCCCCCCCHHHHHHC	31.77	27742792
33	Phosphorylation	PRSVSKESVASMGAD CCCCCHHHHHHCCCC	27.07	23684622
36	Phosphorylation	VSKESVASMGADSGD CCHHHHHHCCCCCCC	18.65	23684622
37	Oxidation	SKESVASMGADSGDD CHHHHHHCCCCCCCC	3.55	17242355
41	Phosphorylation	VASMGADSGDDFASD HHHCCCCCCCCCCCC	43.52	23684622
47	Phosphorylation	DSGDDFASDGSSSRE CCCCCCCCCCCCCHH	42.36	26643407
50	Phosphorylation	DDFASDGSSSREDLS CCCCCCCCCCHHHHH	30.08	26643407
51	Phosphorylation	DFASDGSSSREDLSS CCCCCCCCCHHHHHH	38.66	25293948
52	Phosphorylation	FASDGSSSREDLSSQ CCCCCCCCHHHHHHH	41.19	25293948
57	Phosphorylation	SSSREDLSSQLLRRN CCCHHHHHHHHHHHH	28.49	25293948
58	Phosphorylation	SSREDLSSQLLRRNE CCHHHHHHHHHHHHH	31.95	25293948
75	Phosphorylation	RKLEARLSDYAEQVR HHHHHHHHHHHHHHH	24.03	26643407
77	Phosphorylation	LEARLSDYAEQVRNL HHHHHHHHHHHHHHH	14.52	26643407
536	Phosphorylation	RQLEKGHSSALLQMH HHHHHHCHHHHHHHH	26.44	30352176
537	Phosphorylation	QLEKGHSSALLQMHK HHHHHCHHHHHHHHH	19.77	30352176
652	Phosphorylation	ELKIRPDSELFEVRE HHCCCCCCHHHHHHH	38.59	29514104
745	Phosphorylation	SKPTPKGSIRPSISN CCCCCCCCCCCCCCC	22.88	23984901
749	Phosphorylation	PKGSIRPSISNPRIP CCCCCCCCCCCCCCC	28.88	26643407
751	Phosphorylation	GSIRPSISNPRIPWS CCCCCCCCCCCCCCC	45.15	23684622

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GOGA1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GOGA1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GOGA1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of GOGA1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Large-scale phosphorylation analysis of mouse liver.";
Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-30; SER-36 AND SER-41,AND MASS SPECTROMETRY.
PubMed: 17242355