GOG6A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GOG6A_HUMAN
• UniProt AC: Q9NYA3
• Protein Name: Golgin subfamily A member 6A
• Gene Name: GOLGA6A
• Organism: Homo sapiens (Human).
• Sequence Length: 693
• Protein Sequence: MWPQPYLPPHPMMLEESRQNKLAAAKKKLKEYQQRKSPGIPAGAKTKKKKTDSSPETTTSGGCHSPGDSQYQELAVALESSSVTISQLNENIESLKQQKKQVEHQLEEAKKTNNEIHKAQMERLETINILTLEKADLKTTLYHTKRAARHFEEESKDLAGRLQYSLQRIQELERALCAVSTQQQEEDRSSSCREAVLQRWLQQTIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASHQNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGTEQVERRELGFVQPSGVTDGMRESFTVYESQGAVPNTRHQEMEDVIRLAQKEEEMKVKLLELQELVLPLVGNHEGHGKFLIAAQNPADEPTPGAPAPQELGAAGEQDVFYEVSLDNNVEPAPGAAREGSPHDNPTVQQIVQLSPVMQDT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MWPQPYLPPHPMM --CCCCCCCCCCCCC	26.96	24043423
17	Phosphorylation	HPMMLEESRQNKLAA CCCCCHHHHHHHHHH	29.77	24043423
37	Phosphorylation	KEYQQRKSPGIPAGA HHHHHHHCCCCCCCC	30.46	26714015
45	Acetylation	PGIPAGAKTKKKKTD CCCCCCCCCCCCCCC	61.02	-
47	Acetylation	IPAGAKTKKKKTDSS CCCCCCCCCCCCCCC	62.99	18584635
47	Ubiquitination	IPAGAKTKKKKTDSS CCCCCCCCCCCCCCC	62.99	-
48	Acetylation	PAGAKTKKKKTDSSP CCCCCCCCCCCCCCC	65.81	18584641
48	Ubiquitination	PAGAKTKKKKTDSSP CCCCCCCCCCCCCCC	65.81	-
49	Acetylation	AGAKTKKKKTDSSPE CCCCCCCCCCCCCCC	63.56	18584647
49	Ubiquitination	AGAKTKKKKTDSSPE CCCCCCCCCCCCCCC	63.56	-
131	Phosphorylation	LETINILTLEKADLK HHHCEEEEEECCCHH	29.13	-
144	Phosphorylation	LKTTLYHTKRAARHF HHHHHHHHHHHHHHC	14.52	-
155	Phosphorylation	ARHFEEESKDLAGRL HHHCHHHHHHHHHHH	34.45	21815630
189	Phosphorylation	QQQEEDRSSSCREAV HHHHHHHCHHHHHHH	38.64	-
190	Phosphorylation	QQEEDRSSSCREAVL HHHHHHCHHHHHHHH	34.06	-
329	Phosphorylation	VENNQALSLLSKEQK HHHHHHHHHHCHHHH	30.22	24719451
433	Phosphorylation	QEERLALSQNHKLDK HHHHHHHHHHHHHHH	24.27	22817900
448	Phosphorylation	QLAEPQCSFEDLNNE HHCCCCCCHHHCCHH	26.82	30622161
458	Phosphorylation	DLNNEKKSALQLEQQ HCCHHHHHHHHHHHH	45.33	30622161
531	Phosphorylation	DLESREATSSFMDLP HHHCCHHCCCCCCCC	21.83	30622161
532	Phosphorylation	LESREATSSFMDLPK HHCCHHCCCCCCCCH	28.73	30622161
533	Phosphorylation	ESREATSSFMDLPKE HCCHHCCCCCCCCHH	21.89	30622161
673	Phosphorylation	PGAAREGSPHDNPTV CCCCCCCCCCCCCCH	17.82	25693802
679	Phosphorylation	GSPHDNPTVQQIVQL CCCCCCCCHHHHHHH	36.88	25693802

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GOG6A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GOG6A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GOG6A_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of GOG6A_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.";
Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.;
Anal. Sci. 24:161-166(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-433, AND MASSSPECTROMETRY.
PubMed: 18187866