| UniProt ID | GNAZ_MOUSE | |
|---|---|---|
| UniProt AC | O70443 | |
| Protein Name | Guanine nucleotide-binding protein G(z) subunit alpha | |
| Gene Name | Gnaz | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 355 | |
| Subcellular Localization |
Membrane Lipid-anchor. |
|
| Protein Description | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.. | |
| Protein Sequence | MGCRQSSEEKEAARRSRRIDRHLRSESQRQRREIKLLLLGTSNSGKSTIVKQMKIIHSGGFNLDACKEYKPLIIYNAIDSLTRIIRALAALKIDFHNPDRAYDAVQLFALTGPAESKGEITPELLGVMRRLWADPGAQACFGRSSEYHLEDNAAYYLNDLERIAAPDYIPTVEDILRSRDMTTGIVENKFTFKELTFKMVDVGGQRSERKKWIHCFEGVTAIIFCVELSGYDLKLYEDNQTSRMAESLRLFDSICNNNWFINTSLILFLNKKDLLAEKIRRIPLSVCFPEYKGQNTYEEAAVYIQRQFEDLNRNKETKEIYSHFTCATDTSNIQFVFDAVTDVIIQNNLKYIGLC | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Myristoylation | ------MGCRQSSEE ------CCCCCCHHH | 18.47 | - | |
| 3 | S-palmitoylation | -----MGCRQSSEEK -----CCCCCCHHHH | 3.27 | - | |
| 25 | Phosphorylation | RIDRHLRSESQRQRR HHHHHHHCHHHHHHH | 48.21 | 29899451 | |
| 27 | Phosphorylation | DRHLRSESQRQRREI HHHHHCHHHHHHHHH | 31.73 | 29899451 | |
| 42 | Phosphorylation | KLLLLGTSNSGKSTI EEEEEECCCCCCCHH | 27.48 | 29899451 | |
| 44 | Phosphorylation | LLLGTSNSGKSTIVK EEEECCCCCCCHHHE | 47.57 | 29899451 | |
| 51 | Ubiquitination | SGKSTIVKQMKIIHS CCCCHHHEEEEEEEC | 40.60 | - | |
| 66 | S-palmitoylation | GGFNLDACKEYKPLI CCCCHHHHHHHCCEE | 3.25 | 28680068 | |
| 70 | Ubiquitination | LDACKEYKPLIIYNA HHHHHHHCCEEEHHH | 34.14 | 22790023 | |
| 75 | Phosphorylation | EYKPLIIYNAIDSLT HHCCEEEHHHHHHHH | 7.49 | - | |
| 92 | Ubiquitination | IRALAALKIDFHNPD HHHHHHHCCCCCCCC | 35.19 | 22790023 | |
| 102 | Phosphorylation | FHNPDRAYDAVQLFA CCCCCHHHHHHHHHH | 12.82 | 22871156 | |
| 111 | Phosphorylation | AVQLFALTGPAESKG HHHHHHHHCCCCCCC | 37.38 | 22871156 | |
| 116 | Phosphorylation | ALTGPAESKGEITPE HHHCCCCCCCCCCHH | 48.33 | 22871156 | |
| 117 | Ubiquitination | LTGPAESKGEITPEL HHCCCCCCCCCCHHH | 52.66 | 22790023 | |
| 121 | Phosphorylation | AESKGEITPELLGVM CCCCCCCCHHHHHHH | 13.35 | 22324799 | |
| 140 | S-palmitoylation | ADPGAQACFGRSSEY CCCCHHHHCCCCCEE | 2.18 | 28680068 | |
| 189 | Ubiquitination | TTGIVENKFTFKELT CCCCCCCCEEECEEE | 32.07 | 22790023 | |
| 193 | Ubiquitination | VENKFTFKELTFKMV CCCCEEECEEEEEEE | 49.08 | 22790023 | |
| 272 | Ubiquitination | LILFLNKKDLLAEKI HEEHHCHHHHHHHHH | 53.16 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GNAZ_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GNAZ_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GNAZ_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of GNAZ_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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