dbPTM

GNAT1_BOVIN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GNAT1_BOVIN
UniProt AC	P04695
Protein Name	Guanine nucleotide-binding protein G(t) subunit alpha-1
Gene Name	GNAT1
Organism	Bos taurus (Bovine).
Sequence Length	350
Subcellular Localization	Cell projection, cilium, photoreceptor outer segment . Membrane Peripheral membrane protein .
Protein Description	Functions as signal transducer for the rod photoreceptor RHO. [PubMed: 21285355]
Protein Sequence	MGAGASAEEKHSRELEKKLKEDAEKDARTVKLLLLGAGESGKSTIVKQMKIIHQDGYSLEECLEFIAIIYGNTLQSILAIVRAMTTLNIQYGDSARQDDARKLMHMADTIEEGTMPKEMSDIIQRLWKDSGIQACFDRASEYQLNDSAGYYLSDLERLVTPGYVPTEQDVLRSRVKTTGIIETQFSFKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFIAALSAYDMVLVEDDEVNRMHESLHLFNSICNHRYFATTSIVLFLNKKDVFSEKIKKAHLSICFPDYNGPNTYEDAGNYIKVQFLELNMRRDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	N-myristoyl glycine	------MGAGASAEE ------CCCCCCHHH	32.49	-
2	Myristoylation	------MGAGASAEE ------CCCCCCHHH	32.49	1436039
142	Phosphorylation	CFDRASEYQLNDSAG HHHHHHHCCCCCCCC	18.79	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
142	Y	Phosphorylation	Kinase	SRC	P12931	PSP
142	Y	Phosphorylation	Kinase	SRC	Q9WUD9	PSP

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GNAT1_BOVIN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GNAT1_BOVIN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of GNAT1_BOVIN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GNAT1_BOVIN

Related Literatures of Post-Translational Modification

Myristoylation
Reference	PubMed
"Lipid modification at the N-terminus of photoreceptor G-proteinalpha-subunit."; Kokame K., Fukada Y., Yoshizawa T., Takao T., Shimonishi Y.; Nature 359:749-752(1992). Cited for: MYRISTOYLATION AT GLY-2.	1436039 [Abstract]