GNAS3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GNAS3_MOUSE
• UniProt AC: Q9Z0F1
• Protein Name: Neuroendocrine secretory protein 55
• Gene Name: Gnas {ECO:0000312|MGI:MGI:95777}
• Organism: Mus musculus (Mouse).
• Sequence Length: 257
• Subcellular Localization: Cytoplasmic vesicle, secretory vesicle. Secreted. Neuroendocrine secretory granules..
• Protein Sequence: MDRRSRAQQWRRARHNYNDLCPPIGRRAATALLWLSCSIALLRALASSNARAQQRAAQRRSFLNAHHRSAAAAAAAQVLPESSESESDHEHEEVEPELARPECLEYDQDDYETETDSETEPESDIESETEIETEPETEPETAPTTEPETEPEDERGPRGATFNQSLTQRLHALKLQSADASPRRAQPTTQEPESASEGEEPQRGPLDQDPRDPEEEPEERKEENRQPRRCKTRRPARRRDQSPESPPRKGPIPIRRH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
61	Phosphorylation	QRAAQRRSFLNAHHR HHHHHHHHHHHHHHH	35.95	29899451
61 (in isoform 2)	Phosphorylation	-	35.95	29899451
174	Ubiquitination	TQRLHALKLQSADAS HHHHHHHHCCCCCCC	45.31	22790023
238 (in isoform 2)	Phosphorylation	-	48.94	24759943
241 (in isoform 2)	Phosphorylation	-	60.10	24759943
242	Phosphorylation	PARRRDQSPESPPRK CCCCCCCCCCCCCCC	34.62	24759943
245	Phosphorylation	RRDQSPESPPRKGPI CCCCCCCCCCCCCCC	43.52	24759943

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GNAS3_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GNAS3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GNAS3_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of GNAS3_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.