| UniProt ID | GNA11_MOUSE | |
|---|---|---|
| UniProt AC | P21278 | |
| Protein Name | Guanine nucleotide-binding protein subunit alpha-11 | |
| Gene Name | Gna11 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 359 | |
| Subcellular Localization |
Cell membrane Lipid-anchor. Cytoplasm. |
|
| Protein Description | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Acts as an activator of phospholipase C.. | |
| Protein Sequence | MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAMVRAMETLKILYKYEQNKANALLIREVDVEKVTTFEHQYVNAIKTLWSDPGVQECYDRRREFQLSDSAKYYLTDVDRIATVGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILHSHLVDYFPEFDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 9 | S-palmitoylation | TLESMMACCLSDEVK CHHHHHHHHHCHHHH | 0.99 | 28680068 | |
| 10 | S-palmitoylation | LESMMACCLSDEVKE HHHHHHHHHCHHHHH | 2.71 | 28680068 | |
| 27 | Ubiquitination | RINAEIEKQLRRDKR HHCHHHHHHHHHCHH | 61.36 | 22790023 | |
| 52 | Ubiquitination | LGTGESGKSTFIKQM HHCCCCCCHHHHEEE | 56.45 | 22790023 | |
| 57 | Ubiquitination | SGKSTFIKQMRIIHG CCCHHHHEEEEECCC | 33.57 | - | |
| 72 | Ubiquitination | AGYSEEDKRGFTKLV CCCCHHHHCCCHHHH | 58.67 | 22790023 | |
| 96 | Phosphorylation | AMVRAMETLKILYKY HHHHHHHHHHHHHHH | 21.92 | 28059163 | |
| 101 | Phosphorylation | METLKILYKYEQNKA HHHHHHHHHHHHHCC | 18.26 | 22499769 | |
| 102 | Acetylation | ETLKILYKYEQNKAN HHHHHHHHHHHHCCC | 38.58 | 23954790 | |
| 102 | Ubiquitination | ETLKILYKYEQNKAN HHHHHHHHHHHHCCC | 38.58 | 22790023 | |
| 103 | Phosphorylation | TLKILYKYEQNKANA HHHHHHHHHHHCCCE | 14.80 | 22499769 | |
| 107 | Ubiquitination | LYKYEQNKANALLIR HHHHHHHCCCEEEEE | 42.59 | 22790023 | |
| 120 | Ubiquitination | IREVDVEKVTTFEHQ EEEECHHHCCCCCHH | 44.74 | 22790023 | |
| 158 | Ubiquitination | FQLSDSAKYYLTDVD CCCCCCCEEEECCHH | 38.08 | 22790023 | |
| 252 | Ubiquitination | ENRMEESKALFRTII CCCHHHHHHHHHHHH | 53.00 | 22790023 | |
| 330 | S-nitrosocysteine | IIYSHFTCATDTENI EEEEECEEECCCCCC | 3.62 | - | |
| 330 | S-nitrosylation | IIYSHFTCATDTENI EEEEECEEECCCCCC | 3.62 | 20925432 | |
| 345 | Ubiquitination | RFVFAAVKDTILQLN HHHHHHHHHHHHHHC | 44.41 | - | |
| 356 | Phosphorylation | LQLNLKEYNLV---- HHHCCHHCCCC---- | 16.53 | 11994281 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GNA11_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GNA11_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GNA11_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of GNA11_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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