dbPTM

GLYC4_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GLYC4_ARATH
UniProt AC	O23254
Protein Name	Serine hydroxymethyltransferase 4
Gene Name	SHM4
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	471
Subcellular Localization	Cytoplasm .
Protein Description	Catalyzes the interconversion of serine and glycine..
Protein Sequence	MEPVSSWGNTSLVSVDPEIHDLIEKEKRRQCRGIELIASENFTSFAVIEALGSALTNKYSEGIPGNRYYGGNEFIDEIENLCRSRALEAFHCDPAAWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHLTHGYYTSGGKKISATSIYFESLPYKVNFTTGYIDYDKLEEKALDFRPKLLICGGSAYPRDWDYARFRAIADKVGALLLCDMAHISGLVAAQEAANPFEYCDVVTTTTHKSLRGPRAGMIFYRKGPKPPKKGQPEGAVYDFEDKINFAVFPALQGGPHNHQIGALAVALKQANTPGFKVYAKQVKANAVALGNYLMSKGYQIVTNGTENHLVLWDLRPLGLTGNKVEKLCDLCSITLNKNAVFGDSSALAPGGVRIGAPAMTSRGLVEKDFEQIGEFLSRAVTLTLDIQKTYGKLLKDFNKGLVNNKDLDQLKADVEKFSASYEMPGFLMSEMKYKD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
1	Acetylation	-------MEPVSSWG -------CCCCCCCC	22223895
6	Phosphorylation	--MEPVSSWGNTSLV --CCCCCCCCCCCEE	19376835
10	Phosphorylation	PVSSWGNTSLVSVDP CCCCCCCCCEEECCH	23328941
244	N6-(pyridoxal phosphate)lysine	VVTTTTHKSLRGPRA EEEEECCHHHCCCCC	-
244	Other	VVTTTTHKSLRGPRA EEEEECCHHHCCCCC	-
330	Sulfoxidation	VALGNYLMSKGYQIV HHHHHHHHHCCEEEE	25693801

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GLYC4_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GLYC4_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GLYC4_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
UBP16_ARATH	UBP16	physical	23232097

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GLYC4_ARATH

Related Literatures of Post-Translational Modification