GLPK5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GLPK5_HUMAN
• UniProt AC: Q6ZS86
• Protein Name: Putative glycerol kinase 5
• Gene Name: GK5
• Organism: Homo sapiens (Human).
• Sequence Length: 529
• Protein Sequence: MSGLLTDPEQRAQEPRYPGFVLGLDVGSSVIRCHVYDRAARVCGSSVQKVENLYPQIGWVEIDPDVLWIQFVAVIKEAVKAAGIQMNQIVGLGISTQRATFITWNKKTGNHFHNFISWQDLRAVELVKSWNNSLLMKIFHSSCRVLHFFTRSKRLFTASLFTFTTQQTSLRLVWILQNLTEVQKAVEEENCCFGTIDTWLLYKLTKGSVYATDFSNASTTGLFDPYKMCWSGMITSLISIPLSLLPPVRDTSHNFGSVDEEIFGVPIPIVALVADQQSAMFGECCFQTGDVKLTMGTGTFLDINTGNSLQQTTGGFYPLIGWKIGQEVVCLAESNAGDTGTAIKWAQQLDLFTDAAETEKMAKSLEDSEGVCFVPSFSGLQAPLNDPWACASFMGLKPSTSKYHLVRAILESIAFRNKQLYEMMKKEIHIPVRKIRADGGVCKNGFVMQMTSDLINENIDRPADIDMSCLGAASLAGLAVGFWTDKEELKKLRQSEVVFKPQKKCQEYEMSLENWAKAVKRSMNWYNKT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSGLLTDPE ------CCCCCCCHH	37.84	28270605
6	Phosphorylation	--MSGLLTDPEQRAQ --CCCCCCCHHHHHC	55.33	24719451
81 (in isoform 3)	Ubiquitination	-	12.34	21906983
126	Ubiquitination	QDLRAVELVKSWNNS HHHHHHHHHHHCCHH	4.77	21963094
129	Phosphorylation	RAVELVKSWNNSLLM HHHHHHHHCCHHHHH	27.79	30108239
129	Ubiquitination	RAVELVKSWNNSLLM HHHHHHHHCCHHHHH	27.79	23503661
133	Phosphorylation	LVKSWNNSLLMKIFH HHHHCCHHHHHHHHH	21.48	30108239
152	Phosphorylation	VLHFFTRSKRLFTAS HHHHHHCCCCEEEEE	21.04	24719451
159	Phosphorylation	SKRLFTASLFTFTTQ CCCEEEEECEEEECC	22.43	-
168	Phosphorylation	FTFTTQQTSLRLVWI EEEECCCHHHHHHHH	21.65	-
224	Ubiquitination	ASTTGLFDPYKMCWS CCCCCCCCCCHHHHH	51.14	21963094
227	Ubiquitination	TGLFDPYKMCWSGMI CCCCCCCHHHHHHHH	32.73	23503661
275	Ubiquitination	PIVALVADQQSAMFG CEEEEECCCCHHHHC	39.30	21963094
278	Ubiquitination	ALVADQQSAMFGECC EEECCCCHHHHCCCC	18.97	23503661
360	Ubiquitination	TDAAETEKMAKSLED CCHHHHHHHHHHHCC	52.13	21963094
360 (in isoform 1)	Ubiquitination	-	52.13	21906983
363	Ubiquitination	AETEKMAKSLEDSEG HHHHHHHHHHCCCCC	52.67	23503661
425	Ubiquitination	KQLYEMMKKEIHIPV HHHHHHHHHHCCCCH	46.04	32015554
426	Ubiquitination	QLYEMMKKEIHIPVR HHHHHHHHHCCCCHH	43.96	29967540
474	Phosphorylation	MSCLGAASLAGLAVG HHHHHHHHHHHHHHC	20.44	22210691
504	Ubiquitination	VVFKPQKKCQEYEMS CCCCCCHHHHHHHHC	35.58	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GLPK5_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GLPK5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GLPK5_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of GLPK5_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.