GLMN_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GLMN_MOUSE
• UniProt AC: Q8BZM1
• Protein Name: Glomulin
• Gene Name: Glmn
• Organism: Mus musculus (Mouse).
• Sequence Length: 596
• Protein Description: Essential for normal development of the vasculature. May represent a naturally occurring ligand of the immunophilins FKBP59 and FKBP12. May function as an membrane anchoring protein. May stimulate the p70S6K pathway. May inhibit cell proliferation and increase IL2 production (By similarity)..
• Protein Sequence: MAVEELQSIIKRCQILEEHDFKEEDFGLFQLAGQRCIEDGYINQLLEIIQDEKNKTIIKSMGWNLVGPVVRCLLRGREEDKREECFLIFDLLVKLCNPKELLLGLLELIEEPSGKQISQIILLLLQPLQTVIQKLPNNKAYSVGLALSTLWSQLSLLPVPHSEEQIQADDYGLCQCCKALIEFTKPFVEEVISDKENKENAKLKDELLKFCFKGLKCPLLTAQFLEQSEDVGNDPFRCFASEIIGFLSKIGHPVPQIILNHGRKKRTWDYLEFEEEEDKQLAESVASLTYLVFVQGIGIDQLPMVLSPSYLLQLNMEHIEVFLQRTEQSIYSKGLELLETSLLRLEDNSLCYQYLEIKSFLAVPQGLVKVMTLCPIETLRKKGLSMLQLFIDKLDSQGKYTLFRCLLNTSNHSGVEAFVIQNIKNQIDLSFKKTYNKWFAGAQLISLLDLVLSLPEGAETDLLQNSDRIMASLNLLRYLVIKDNEDDNQTGLWTELGKIENNFLKPLHIGLNMSKAHYEAEIKNSQQNNQVASMCKGVCSVTVGGEEIPSMPPEMQLKVLHSALFTFDLIESVLARVEELIEIKSKSTSEENVGIK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAVEELQSI ------CCHHHHHHH	19.89	-
8	Phosphorylation	MAVEELQSIIKRCQI CCHHHHHHHHHHHHH	38.62	23140645
430	Phosphorylation	IKNQIDLSFKKTYNK HHHHCCCCCHHHCHH	31.13	30635358
434	Phosphorylation	IDLSFKKTYNKWFAG CCCCCHHHCHHHHHH	32.68	30635358
435	Phosphorylation	DLSFKKTYNKWFAGA CCCCHHHCHHHHHHH	24.51	30635358
587	Phosphorylation	LIEIKSKSTSEENVG HHHHHCCCCCCCCCC	44.23	30635358
588	Phosphorylation	IEIKSKSTSEENVGI HHHHCCCCCCCCCCC	43.84	30635358
589	Phosphorylation	EIKSKSTSEENVGIK HHHCCCCCCCCCCCC	50.43	30635358

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GLMN_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GLMN_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GLMN_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BIRC2_MOUSE	Birc2	physical	29191979

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.