GLGL1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GLGL1_ARATH
• UniProt AC: P55229
• Protein Name: Glucose-1-phosphate adenylyltransferase large subunit 1, chloroplastic
• Gene Name: ADG2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 522
• Subcellular Localization: Plastid, chloroplast.
• Protein Description: This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP..
• Protein Sequence: MVVSADCRISLSAPSCIRSSSTGLTRHIKLGSFCNGELMGKKLNLSQLPNIRLRSSTNFSQKRILMSLNSVAGESKVQELETEKRDPRTVASIILGGGAGTRLFPLTKRRAKPAVPIGGAYRLIDVPMSNCINSGINKVYILTQYNSASLNRHLARAYNSNGLGFGDGYVEVLAATQTPGESGKRWFQGTADAVRQFHWLFEDARSKDIEDVLILSGDHLYRMDYMDFIQDHRQSGADISISCIPIDDRRASDFGLMKIDDKGRVISFSEKPKGDDLKAMAVDTTILGLSKEEAEKKPYIASMGVYVFKKEILLNLLRWRFPTANDFGSEIIPFSAKEFYVNAYLFNDYWEDIGTIRSFFEANLALTEHPGAFSFYDAAKPIYTSRRNLPPSKIDNSKLIDSIISHGSFLTNCLIEHSIVGIRSRVGSNVQLKDTVMLGADYYETEAEVAALLAEGNVPIGIGENTKIQECIIDKNARVGKNVIIANSEGIQEADRSSDGFYIRSGITVILKNSVIKDGVVI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
57	Phosphorylation	NIRLRSSTNFSQKRI CCCCCCCCCCCHHHH	41.34	19880383
60	Phosphorylation	LRSSTNFSQKRILMS CCCCCCCCHHHHHHH	36.54	19880383
89	Phosphorylation	TEKRDPRTVASIILG HCCCCCHHEEEEEEC	26.30	24299221
101	Phosphorylation	ILGGGAGTRLFPLTK EECCCCHHHCCCCCC	24.54	29654922
190	Phosphorylation	GKRWFQGTADAVRQF CCCEECCCHHHHHHH	15.58	25561503
252	Phosphorylation	PIDDRRASDFGLMKI ECCCCCHHHCCCEEE	31.49	25561503
267	Phosphorylation	DDKGRVISFSEKPKG CCCCCEEEEECCCCC	21.62	25561503
428	Phosphorylation	GIRSRVGSNVQLKDT EECCCCCCCCEEECE	30.85	19376835

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GLGL1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GLGL1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GLGL1_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of GLGL1_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks.";
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.;
Plant Physiol. 150:889-903(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-428, AND MASSSPECTROMETRY.
PubMed: 19376835