| UniProt ID | GLD2_MOUSE | |
|---|---|---|
| UniProt AC | Q91YI6 | |
| Protein Name | Poly(A) RNA polymerase GLD2 | |
| Gene Name | Papd4 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 484 | |
| Subcellular Localization | Cytoplasm . Nucleus . | |
| Protein Description | Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Does not play a role in replication-dependent histone mRNA degradation (By similarity).. | |
| Protein Sequence | MFPNSILGRPPFTPTHQQHNNFFALSPTLYSHQQLIDAQFNFQNVDLSRAVSLQPLTYGTVSPIQTSTSPLFRGRKRISDEKAFPLDGKRQRFHSPHQEPTIINQLVPLSGDRRYSMPPLFHTHYIPDIVRCVPPLREIPLLEPREITLPEAKDKLSQQILELFETCQQQASDLKKKELCRAQLQREIQLLFPQSRLFLVGSSLNGFGARSSDGDLCLVVKEEPCFFQVNQKTEARHILTLVHKHFCTRLSGYIERPQLIRAKVPIVKFRDKVSCVEFDLNVNNTVGIRNTFLLRTYAYLENRVRPLVLVIKKWASHHDINDASRGTLSSYSLVLMVLHYLQTLPEPILPSLQKIYPESFSTSVQLHLVHHAPCNVPPYLSKNESSLGDLLLGFLKYYATEFDWNTQMISVREAKAIPRPDDMEWRNKYICVEEPFDGTNTARAVHEKQKFDMIKDQFLKSWQRLKNKRDLNSVLPLRAATLKR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 57 | Phosphorylation | AVSLQPLTYGTVSPI CEEECCCCCCCCCCC | 26.96 | 26643407 | |
| 58 | Phosphorylation | VSLQPLTYGTVSPIQ EEECCCCCCCCCCCC | 20.62 | 26643407 | |
| 60 | Phosphorylation | LQPLTYGTVSPIQTS ECCCCCCCCCCCCCC | 13.85 | 26643407 | |
| 62 | Phosphorylation | PLTYGTVSPIQTSTS CCCCCCCCCCCCCCC | 19.00 | 26643407 | |
| 66 | Phosphorylation | GTVSPIQTSTSPLFR CCCCCCCCCCCCCCC | 34.39 | 26643407 | |
| 67 | Phosphorylation | TVSPIQTSTSPLFRG CCCCCCCCCCCCCCC | 15.54 | 26643407 | |
| 68 | Phosphorylation | VSPIQTSTSPLFRGR CCCCCCCCCCCCCCC | 37.44 | 26643407 | |
| 69 | Phosphorylation | SPIQTSTSPLFRGRK CCCCCCCCCCCCCCC | 21.26 | 26643407 | |
| 95 | Phosphorylation | GKRQRFHSPHQEPTI CCCCCCCCCCCCCCC | 22.74 | 25159016 | |
| 101 | Phosphorylation | HSPHQEPTIINQLVP CCCCCCCCCCHHEEE | 33.46 | 25159016 | |
| 110 | Phosphorylation | INQLVPLSGDRRYSM CHHEEECCCCCCCCC | 32.36 | 25159016 | |
| 116 | Phosphorylation | LSGDRRYSMPPLFHT CCCCCCCCCCCCEEC | 24.01 | 27600695 | |
| 410 | Phosphorylation | DWNTQMISVREAKAI CCCCCEEEHHHHHCC | 15.13 | 26487105 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GLD2_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GLD2_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GLD2_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of GLD2_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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