GIN1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GIN1_HUMAN
• UniProt AC: Q9NXP7
• Protein Name: Gypsy retrotransposon integrase-like protein 1
• Gene Name: GIN1
• Organism: Homo sapiens (Human).
• Sequence Length: 522
• Protein Sequence: MVRSGKNGDLHLKQIAYYKRTGEYHSTTLPSERSGIRRAAKKFVFKEKKLFYVGKDRKQNRLVIVSEEEKKKVLRECHENDSGAHHGISRTLTLVESNYYWTSVTNDVKQWVYACQHCQVAKNTVIVAPKQHLLKVENPWSLVTVDLMGPFHTSNRSHVYAIIMTDLFTKWIVILPLCDVSASEVSKAIINIFFLYGPPQKIIMDQRDEFIQQINIELYRLFGIKQIVISHTSGTVNPTESTPNTIKAFLSKHCADHPNNWDDHLSAVSFAFNVTHLEPTKNTPYFQMFSRNPYMPETSDSLHEVDGDNTSMFAKILDAIKEADKIMENKTTSLGQMENNNLDELNKSKIIVKKKPKQLNPFHLKVGHEVLRQRKNWWKDGRFQSEWVGPCVIDYITESGCAVLRDNTGVRLKRPIKMSHLKPYIRESSEQESLYLLQGSVVADHDYIGLPEIPIGAYQANILVEDATIGIVDNELLTSSKDRELLEYRNTKISPLIDDHSSLEKQTFSLLDSSNQVLEYLS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
21	Phosphorylation	QIAYYKRTGEYHSTT EEEEEECCCCCCCCC	30.16	24043423
24	Phosphorylation	YYKRTGEYHSTTLPS EEECCCCCCCCCCCC	11.47	24043423
26	Phosphorylation	KRTGEYHSTTLPSER ECCCCCCCCCCCCCC	23.37	24043423
27	Phosphorylation	RTGEYHSTTLPSERS CCCCCCCCCCCCCCH	21.02	24043423
28	Phosphorylation	TGEYHSTTLPSERSG CCCCCCCCCCCCCHH	39.42	24043423
31	Phosphorylation	YHSTTLPSERSGIRR CCCCCCCCCCHHHHH	49.07	24719451
34	Phosphorylation	TTLPSERSGIRRAAK CCCCCCCHHHHHHHH	34.22	24043423
178	Ubiquitination	WIVILPLCDVSASEV HHHHHHCCCCCHHHH	4.60	22817900
183	Ubiquitination	PLCDVSASEVSKAII HCCCCCHHHHHHHHH	30.90	22817900
218 (in isoform 3)	Phosphorylation	-	2.39	30622161
294	Phosphorylation	QMFSRNPYMPETSDS CCCCCCCCCCCCCCC	28.93	23532336
301	Phosphorylation	YMPETSDSLHEVDGD CCCCCCCCCCCCCCC	31.24	23532336
325	Ubiquitination	DAIKEADKIMENKTT HHHHHHHHHHHCCCC	51.50	22817900
330	Ubiquitination	ADKIMENKTTSLGQM HHHHHHCCCCCHHHH	39.61	22817900
330 (in isoform 1)	Ubiquitination	-	39.61	21906983
330 (in isoform 2)	Ubiquitination	-	39.61	21906983
345	Ubiquitination	ENNNLDELNKSKIIV HCCCHHHHHHHCEEE	11.04	29967540
419	Phosphorylation	LKRPIKMSHLKPYIR ECCCCCHHHCCCCCC	22.21	-
491	Phosphorylation	ELLEYRNTKISPLID HHHHHCCCCCCCCCC	22.28	23312004
492	Ubiquitination	LLEYRNTKISPLIDD HHHHCCCCCCCCCCC	44.74	29967540
494	Phosphorylation	EYRNTKISPLIDDHS HHCCCCCCCCCCCCH	18.40	27050516
501	Phosphorylation	SPLIDDHSSLEKQTF CCCCCCCHHHCHHHH	43.54	23186163
502	Phosphorylation	PLIDDHSSLEKQTFS CCCCCCHHHCHHHHH	36.81	14702039

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GIN1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GIN1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GIN1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of GIN1_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.