GIMA1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GIMA1_MOUSE
• UniProt AC: P70224
• Protein Name: GTPase IMAP family member 1
• Gene Name: Gimap1
• Organism: Mus musculus (Mouse).
• Sequence Length: 277
• Subcellular Localization: Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Golgi apparatus membrane.
• Protein Description: May regulate lymphocyte survival. Required for normal levels of mature T-lymphocytes and mature B-cells..
• Protein Sequence: MPQLRLILVGRTGTGKSATGNSILGQKCFLSRLGAVPVTRSCTLASRMWAGWQVEVVDTPDIFSSEIPRTDPGCVETARCFVLSAPGPHALLLVTQLGRFTMQDSQALAAVKRLFGKQVMARTVVVFTRQEDLAGDSLQDYVHCTDNRALRDLVAECGGRVCALNNRATGSEREAQAEQLLGMVACLVREHGGAHYSNEVYELVQDTRCADPQDQVAKVAEIVAERMQRRTRLLAGLWGWRKFYWKGWRRGFSVFLGVAILIYLLFYRKGFGDQNNR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Phosphorylation	ILVGRTGTGKSATGN EEEECCCCCCCCCCC	40.60	20139300
19	Phosphorylation	TGTGKSATGNSILGQ CCCCCCCCCCCHHCC	43.94	15851034
105	Phosphorylation	GRFTMQDSQALAAVK CCCCCCHHHHHHHHH	10.64	20139300

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GIMA1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GIMA1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GIMA1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of GIMA1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.