dbPTM

GHT5_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GHT5_SCHPO
UniProt AC	P78831
Protein Name	High-affinity glucose transporter ght5
Gene Name	ght5
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	546
Subcellular Localization	Membrane Multi-pass membrane protein.
Protein Description	High-affinity glucose transporter..
Protein Sequence	MGKNLTIVMLVFVSMAGWMFGADTGSIGGITNMRDFQSRFADRYNPVTDSYSYSSARQGLITGMVNVGSFFGCFLSSPLMDRIGKRTSIMFWTIVYLIGIILQVTAVPSWVQIMVAKIWTGLSIGALSVLAPGFQSEVAPADLRGTIVTTYQLAVTGGIFIAACINMGTHKLHKTAQWRVSMGINLLWGIITFIGISFLPESPRYLISVGRDEEALQIMAKNNDLPIEHEVIQTEYHVIKSDCEAELAGGPATWPEIFGPDIRYRTFLGLGVMSLQQLTGDNYYFYYGFEVFEGTGMNSPYLSALILDAVNFGCTFGGLFVLEFFGRRMPLIIGALWQSITFFIYAAVGNRALTRKNGTSNHRAGAVMIVFSCLFIFSFAQTWGPAAYVIVGESYPIRYRSKCAAVATTGNWLWGFLISFFTPFITNSIGFKYGYIFAACNLCAACIIFLFAHETKGLTLEEINELYISGAKPWMPRPKNLGNFTKQQEEVREKSRGVQGESAAHLENVDGEEGIEDSSNDISSTTSSDGRAKPESSYHDQEEQFA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
357	N-linked_Glycosylation	NRALTRKNGTSNHRA CHHHHCCCCCCCCHH	56.54	-
485	Phosphorylation	PKNLGNFTKQQEEVR CCCCCCHHHHHHHHH	31.76	24763107
518	Phosphorylation	GEEGIEDSSNDISST CCCCCCCCCCCCCCC	20.46	25720772
519	Phosphorylation	EEGIEDSSNDISSTT CCCCCCCCCCCCCCC	51.33	25720772
523	Phosphorylation	EDSSNDISSTTSSDG CCCCCCCCCCCCCCC	25.21	29996109
524	Phosphorylation	DSSNDISSTTSSDGR CCCCCCCCCCCCCCC	35.72	25720772
525	Phosphorylation	SSNDISSTTSSDGRA CCCCCCCCCCCCCCC	24.73	29996109
526	Phosphorylation	SNDISSTTSSDGRAK CCCCCCCCCCCCCCC	28.34	29996109
527	Phosphorylation	NDISSTTSSDGRAKP CCCCCCCCCCCCCCC	26.90	25720772
528	Phosphorylation	DISSTTSSDGRAKPE CCCCCCCCCCCCCCC	41.83	28889911
536	Phosphorylation	DGRAKPESSYHDQEE CCCCCCCCCCCCCHH	44.73	25720772
537	Phosphorylation	GRAKPESSYHDQEEQ CCCCCCCCCCCCHHH	25.48	28889911
538	Phosphorylation	RAKPESSYHDQEEQF CCCCCCCCCCCHHHC	20.77	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GHT5_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GHT5_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GHT5_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of GHT5_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GHT5_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-528 AND SER-537, ANDMASS SPECTROMETRY.	18257517 [Abstract]