GGT1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GGT1_ARATH
• UniProt AC: Q9LR30
• Protein Name: Glutamate--glyoxylate aminotransferase 1
• Gene Name: GGAT1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 481
• Subcellular Localization: Peroxisome .
• Protein Description: Catalyzes the glutamate:glyoxylate (GGT or GGAT), alanine:glyoxylate (AGT), alanine:2-oxoglutarate (AKT) and glutamate:pyruvate (GPT) aminotransferase reactions in peroxisomes. Required for abscisic acid (ABA)- and stress-mediated responses in an H(2)O(2)-dependent manner. Function as a photorespiratory aminotransferase that modulates amino acid content during photorespiration (GGAT activity); promotes serine, glycine and citrulline metabolism in response to light..
• Protein Sequence: MALKALDYDTLNENVKKCQYAVRGELYLRASELQKEGKKIIFTNVGNPHALGQKPLTFPRQVVALCQAPFLLDDPNVGMLFPADAIARAKHYLSLTSGGLGAYSDSRGLPGVRKEVAEFIQRRDGYPSDPELIFLTDGASKGVMQILNCVIRGNGDGILVPVPQYPLYSATISLLGGTLVPYYLDESENWGLDVANLRQSVAQARSQGITVRAMVIINPGNPTGQCLSEANIREILKFCYNEKLVLLGDEVYQQNIYQDERPFISSKKVLMEMGSPFSKEVQLVSFHTVSKGYWGECGQRGGYFEMTNLPPRVVEEIYKVASIALSPNVSAQIFMGLMVNPPKPGDISYDQFARESKGILESLRRRARLMTDGFNSCKNVVCNFTEGAMYSFPQIRLPTGALQAAKQAGKVPDVFYCLKLLEATGISTVPGSGFGQKEGVFHLRTTILPAEDEMPEIMDSFKKFNDEFMTQYDNNFGYSKM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MALKALDYDTLNENV CCCCCCCHHHHCHHH	16.21	19880383
275	Phosphorylation	KVLMEMGSPFSKEVQ HHHHHCCCCCCCEEE	22.82	25561503
291	N6-(pyridoxal phosphate)lysine	VSFHTVSKGYWGECG EEEEEECCCCCCCCC	52.24	-
291	Other	VSFHTVSKGYWGECG EEEEEECCCCCCCCC	52.24	-
399	Phosphorylation	FPQIRLPTGALQAAK CCCCCCCHHHHHHHH	39.41	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GGT1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GGT1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GGT1_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of GGT1_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.