dbPTM

GELS_CHICK - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GELS_CHICK
UniProt AC	O93510
Protein Name	Gelsolin
Gene Name	GSN
Organism	Gallus gallus (Chicken).
Sequence Length	778
Subcellular Localization	Secreted. Cytoplasm, cytoskeleton. A cytoplasmic form may also exist..
Protein Description	Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis (By similarity)..
Protein Sequence	MGKQGFGYIFLTIFCTMALKLNCVSSVSVAGLGYVVTAAVVLSAVPVSMVEHAEFSKAGKEPGLQIWRIEKFDLVPVPKNLYGDFFTGDSYLVLNTIRQRSGNLQYDLHFWLGDESSQDERGAAAIFTVQMDDYLQGKAVQHREVQGHESSTFLGYFKSGIKYKAGGVASGFRHVVPNEVTVQRLLQVKGRRTVRATEVPVSWESFNTGDCFILDLGSNIYQWCGSNSNRQERLKATVLAKGIRDNEKNGRAKVFVSEEGAEREEMLQVLGPKPSLPQGASDDTKTDTANRKLAKLYKVSNGAGNMAVSLVADENPFSQAALNTEDCFILDHGTDGKIFVWKGRSANSDERKAALKTATDFIDKMGYPKHTQVQVLPESGETPLFKQFFKNWRDKDQTEGLGEAYISGHVAKIEKVPFDAATLHTSRAMAAQHGMEDDGSGKKQIWRIEGSEKVPVDPATYGQFYGGDSYIILYDYRHAGKQGQIIYTWQGAHSTQDEIATSAFLTVQLDEELGGSPVQKRVVQGKEPPHLMSMFGGKPLIVYKGGTSREGGQTTPAQTRLFQVRSSTSGATRAVELDPAASQLNSNDAFVLKTPSAAYLWVGRGSNSAELSGAQELLKVLGARPVQVSEGREPDNFWVALGGKAPYRTSPRLKDKKMDAYPPRLFACSNKSGRFTIEEVPGDLTQDDLATDDVMILDTWDQVFVWIGKDAQEEEKTEALKSAKRYIETDPASRDKRTPVTLVKQGLEPPTFSGWFLGWDDDYWSVDPLQRAMADVDV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of GELS_CHICK !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GELS_CHICK !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GELS_CHICK !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GELS_CHICK !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of GELS_CHICK !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GELS_CHICK

Related Literatures of Post-Translational Modification