GCY3E_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GCY3E_DROME
• UniProt AC: Q07553
• Protein Name: Guanylate cyclase 32E
• Gene Name: Gyc32E
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 1163
• Subcellular Localization: Membrane; Single-pass type I membrane protein.
• Protein Sequence: MPGPCASAAAFSCILVLLLLGCQRSNPLAAGATVSSMRRLTDTINIGFLAEYSQMRVTLGGLPLAIEDVNKNPNLLPGKKLAFKPVDIGHKMSAYRVKPLRAMTQMREAGVTAFIGPDESCTTEALLASAWNTPMLSFKCSDPIVSNKSTFHTFARTLAPASKVSKSVISLLNAFHWNKFSIVVSSKPIWGSDVARAIQELAEARNFTISHFKYISDYIPTTKTLSQIDKIIEETYATTRIYVFIGEHIAMVDFVRGLQNRRLLESGDYIVVSVDDEIYDSNRRVNIMERNYLDPYIRKEKSKSLDKISFRSVIKISMTYPQNPHIRVPIYGLHLYDSVMIYVRAITEVLRLGGDIYDGNLVMSHIFNRSYHSIQGFDVYIDSNGDAEGNYTVITLQNDVGSGASIGSLAKMSMQPVGFFAYDKNSVIPEFRYIKNDRPIQWLNGRPPLAEPLCGFHGELCPRKKLDWRYLVSGPLCALVVVVAIALLIKHYRYEQTLAGLLWKVDMKDVTVINLGEYNNPTNKNIFQICRQSILVVGEPNKRSFTNIALFRGNIVAMKKIHKKSVDITRSIRKELKLMREVRHENIINFIGASTDHGSVIIFTTYCARGSLEDVLANEDLHLDHMFISSLVSDILKGMIYLHDSEIISHGNLRSSNCLIDSRWVCQISDFGLHELKAGQEEPNKSELELKRALCMAPELLRDAYRPGRGSQKGDVYSFGILLYEMIGRKGPWGDTAYSKEEIIQFVKCPEMLQHGVFRPALTHTHLDIPDYIRKCLCQCWDEDPEVRPDIRLVRMHLKELQAGLKPNIFDNMLSIMEKYAYNLEGLVQERTNLLYEEKKKTDMLLYQMLPRPVAELLKRGDPVEAECFDCVTILFSDIVGFTELCTTSTPFEVVEMLNDWYTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGSRHAGEIASLALHLLETVGNLKIRHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGDSMRIHISEATYQLLQVIGSYVCIERGLTSIKGKGDMRTYWLTKRQQPELTPDLISTVDTLDTYCSGPRESMEVSVHQYCSPASNNYRLGSCNCDTKCLYSRRSDDNVTNSHGTSEFPKVSEPAQVNCNQLCVCRLNSSQMFNNRGPRSAPSITFRL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
147	N-linked_Glycosylation	CSDPIVSNKSTFHTF ECCCCCCCCCHHHHH	31.25	-
206	N-linked_Glycosylation	QELAEARNFTISHFK HHHHHHCCCCHHHHH	45.52	-
368	N-linked_Glycosylation	LVMSHIFNRSYHSIQ CEEHHHHCCCCCCCC	31.24	-
390	N-linked_Glycosylation	SNGDAEGNYTVITLQ CCCCCCCCEEEEEEE	22.32	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GCY3E_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GCY3E_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GCY3E_DROME !!

Protein-Protein Interaction

Oops, there are no PPI records of GCY3E_DROME !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.