| UniProt ID | GCSP2_ARATH | |
|---|---|---|
| UniProt AC | O80988 | |
| Protein Name | Glycine dehydrogenase (decarboxylating) 2, mitochondrial | |
| Gene Name | GLDP2 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 1044 | |
| Subcellular Localization | Mitochondrion . | |
| Protein Description | The glycine decarboxylase (GDC) or glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity).. | |
| Protein Sequence | MERARRLAYRGIVKRLVNETKRHRNGESSLLPTTTVTPSRYVSSVSSFLHRRRDVSGSAFTTSGRNQHQTRSISVDALKPSDTFPRRHNSATPDEQAQMANYCGFDNLNTLIDSTVPKSIRLDSMKFSGIFDEGLTESQMIEHMSDLASKNKVFKSFIGMGYYNTHVPPVILRNIMENPAWYTQYTPYQAEISQGRLESLLNYQTVITDLTGLPMSNASLLDEGTAAAEAMAMCNNILKGKKKTFVIASNCHPQTIDVCKTRADGFDLKVVTVDIKDVDYSSGDVCGVLVQYPGTEGEVLDYGEFVKNAHANGVKVVMATDLLALTMLKPPGEFGADIVVGSGQRFGVPMGYGGPHAAFLATSQEYKRMMPGRIIGVSVDSSGKQALRMAMQTREQHIRRDKATSNICTAQALLANMTAMYAVYHGPEGLKSIAQRVHGLAGVFALGLKKLGTAQVQDLPFFDTVKVTCSDATAIFDVAAKKEINLRLVDSNTITVAFDETTTLDDVDKLFEVFASGKPVQFTAESLAPEFNNAIPSSLTRESPYLTHPIFNMYHTEHELLRYIHKLQNKDLSLCHSMIPLGSCTMKLNATTEMMPVTWPSFTNMHPFAPVEQAQGYQEMFTNLGELLCTITGFDSFSLQPNAGAAGEYAGLMVIRAYHMSRGDHHRNVCIIPVSAHGTNPASAAMCGMKIVAVGTDAKGNINIEELRNAAEANKDNLAALMVTYPSTHGVYEEGIDEICNIIHENGGQVYMDGANMNAQVGLTSPGFIGADVCHLNLHKTFCIPHGGGGPGMGPIGVKQHLAPFLPSHPVIPTGGIPEPEQTSPLGTISAAPWGSALILPISYTYIAMMGSGGLTDASKIAILNANYMAKRLESHYPVLFRGVNGTVAHEFIIDLRGFKNTAGIEPEDVAKRLMDYGFHGPTMSWPVPGTLMIEPTESESKAELDRFCDALISIREEISQIEKGNADPNNNVLKGAPHPPSLLMADTWKKPYSREYAAFPAPWLRSSKFWPTTGRVDNVYGDRNLVCTLQPANEEQAAAAVSA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 43 | Phosphorylation | VTPSRYVSSVSSFLH CCHHHHHHHHHHHHH | 6.16 | 25561503 | |
| 44 | Phosphorylation | TPSRYVSSVSSFLHR CHHHHHHHHHHHHHC | 21.51 | 29654922 | |
| 46 | Phosphorylation | SRYVSSVSSFLHRRR HHHHHHHHHHHHCCC | 6.56 | 25561503 | |
| 47 | Phosphorylation | RYVSSVSSFLHRRRD HHHHHHHHHHHCCCC | 5.21 | 25561503 | |
| 125 | Sulfoxidation | KSIRLDSMKFSGIFD CCEECCCCEECCCCC | 8.25 | 25693801 | |
| 780 | N6-(pyridoxal phosphate)lysine | VCHLNLHKTFCIPHG EEECEEECEEEECCC | 27.84 | - | |
| 780 | Other | VCHLNLHKTFCIPHG EEECEEECEEEECCC | 27.84 | - | |
| 869 | Sulfoxidation | AILNANYMAKRLESH HHHCHHHHHHHHHHH | 53.70 | 25693801 | |
| 900 | Acetylation | IIDLRGFKNTAGIEP EEECCCCCCCCCCCH | 41.54 | 24727099 | |
| 902 | Phosphorylation | DLRGFKNTAGIEPED ECCCCCCCCCCCHHH | 52.94 | 29797451 | |
| 1007 | Phosphorylation | FPAPWLRSSKFWPTT CCCHHHHCCCCCCCC | 32.26 | 25561503 | |
| 1008 | Phosphorylation | PAPWLRSSKFWPTTG CCHHHHCCCCCCCCC | 20.93 | 25561503 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GCSP2_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GCSP2_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GCSP2_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of GCSP2_ARATH !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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