dbPTM

GCSH3_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GCSH3_ARATH
UniProt AC	Q9LQL0
Protein Name	Glycine cleavage system H protein 3, mitochondrial
Gene Name	GDH3
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	166
Subcellular Localization	Mitochondrion .
Protein Description	The glycine decarboxylase (GDC) or glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)..
Protein Sequence	MALRMWASSTANALKLSSSASKSHLLPAFSISRCFSSVLEGLKYANSHEWVKHEGSVATIGITDHAQDHLGEVVFVELPEANSSVSKEKSFGAVESVKATSEILSPISGEVIEVNTKLTESPGLINSSPYEDGWMIKVKPSSPAELEALMGPKEYTKFCEEEDAAH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
23	Phosphorylation	LSSSASKSHLLPAFS HCCCCCHHHCCHHHH	19376835
30	Phosphorylation	SHLLPAFSISRCFSS HHCCHHHHHHHHHHH	19376835
32	Phosphorylation	LLPAFSISRCFSSVL CCHHHHHHHHHHHHH	19376835
98	N6-lipoyllysine	FGAVESVKATSEILS CCHHHHHHHHHHHHC	-
98	Lipoylation	FGAVESVKATSEILS CCHHHHHHHHHHHHC	-
141	Phosphorylation	WMIKVKPSSPAELEA EEEEECCCCHHHHHH	23776212
142	Phosphorylation	MIKVKPSSPAELEAL EEEECCCCHHHHHHH	23776212
150	Sulfoxidation	PAELEALMGPKEYTK HHHHHHHHCCHHHHH	25693801
153	Acetylation	LEALMGPKEYTKFCE HHHHHCCHHHHHHHH	24727099

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GCSH3_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GCSH3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GCSH3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of GCSH3_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GCSH3_ARATH

Related Literatures of Post-Translational Modification