GCSH1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GCSH1_ARATH
• UniProt AC: P25855
• Protein Name: Glycine cleavage system H protein 1, mitochondrial
• Gene Name: GDH1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 165
• Subcellular Localization: Mitochondrion .
• Protein Description: The glycine decarboxylase (GDC) or glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein..
• Protein Sequence: MALRMWASSTANALKLSSSVSKSHLSPFSFSRCFSTVLEGLKYANSHEWVKHEGSVATIGITAHAQDHLGEVVFVELPEDNTSVSKEKSFGAVESVKATSEILSPISGEIIEVNKKLTESPGLINSSPYEDGWMIKVKPSSPAELESLMGPKEYTKFCEEEDAAH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
97	N6-lipoyllysine	FGAVESVKATSEILS CCCHHHHCHHHHHHC	56.05	-
97	Lipoylation	FGAVESVKATSEILS CCCHHHHCHHHHHHC	56.05	-
140	Phosphorylation	WMIKVKPSSPAELES EEEEECCCCHHHHHH	43.14	23776212
141	Phosphorylation	MIKVKPSSPAELESL EEEECCCCHHHHHHH	36.33	30291188
149	Sulfoxidation	PAELESLMGPKEYTK HHHHHHHHCCHHHHH	13.87	25693801
152	Acetylation	LESLMGPKEYTKFCE HHHHHCCHHHHHHHH	58.59	24727099

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GCSH1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GCSH1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GCSH1_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of GCSH1_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.