GCP2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GCP2_ARATH
• UniProt AC: Q9M1S8
• Protein Name: Probable glutamate carboxypeptidase AMP1 {ECO:0000305}
• Gene Name: AMP1 {ECO:0000303|PubMed:11549767}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 705
• Subcellular Localization: Endoplasmic reticulum membrane ; Single-pass type II membrane protein .
• Protein Description: May modulate the level of one or more small signaling molecules that have a role in regulating meristem function. May play a role in balancing and restricting the meristem-promoting activity of auxin signaling. [PubMed: 17553903 Involved in ethylene and giberellin (GA) signaling pathways or in a parallel pathway controlling cell and hypocotyl elongation and cellular organization]
• Protein Sequence: MSQPLTTRPTVTGISIIPFRQPPPLCSFLFVIVLFVATFYTLHHPDAVTPPLLFSRNAYNALRLRRLFLSSASNATISSYLRELTRHPHLAGTKPSLDTLHYVFNHFQSLGLETHVAEYEALLSYPTHISVTASFSNTTTLEFDLNDVPGDSPVVRPYHAYSPSGSAQGNVVFVNHGEERDYHALESIGVSVKGCVVLARKGENLGRGAIVKIAEAKGALGVLIYAENDGGGFGGIERGTVMRGIGDPVSPGWPGVVGGEKLSLDDELVTRRFPKIPSLPLSLRNAEIILASLGGARAPLEWRNSGRVGPGQRVGPGRMVINMTFQGEMKMKKINNVVVTIRGSEEADRYVILGNHRDAWTYGAVDPNSGTSALLDISRRFALLLKSGWRPRRTILLCSWDAEEFGMIGSTEWIEENVLNLGASAVAYLNVDCAVQGSGFFAGATPQLDGLLVDVLKLVQDPDAVGLTVEETFKSQNNIIQRLSRVDSDFSGFLHHAGIPSIDMYYGADYPVYHTAFDSYDWMIHNADPLFHRHVAMAGIWGLLGILLADEPLIPFDYISYADQLQAHRDKLSKLLEGKVSVNPLSMAIQEFSLVAKEAADEAKKLKGKSYSKNDVAAAAKRRELNDRLMLVERGFLDAEGIKGKEWFKHLVYGPAAEPESKLGFFPGIADAIAMNASEGIIEHEIWRVARAIQRASKALKGGFT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
74	N-linked_Glycosylation	LFLSSASNATISSYL HHHHCCCCCCHHHHH	40.60	-
137	N-linked_Glycosylation	SVTASFSNTTTLEFD EEEEEECCCEEEEEE	39.16	-
322	N-linked_Glycosylation	GPGRMVINMTFQGEM CCCCEEEEEEEECCE	16.42	-
581	Phosphorylation	KLLEGKVSVNPLSMA HHHCCCCCCCHHHHH	21.47	23172892
586	Phosphorylation	KVSVNPLSMAIQEFS CCCCCHHHHHHHHHH	13.87	23172892
593	Phosphorylation	SMAIQEFSLVAKEAA HHHHHHHHHHHHHHH	22.60	23172892
676	N-linked_Glycosylation	IADAIAMNASEGIIE HHHHHHCCCCCCHHH	31.15	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GCP2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GCP2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GCP2_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of GCP2_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.