dbPTM

GCM2_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GCM2_DROME
UniProt AC	Q9VLA2
Protein Name	Transcription factor glial cells missing 2
Gene Name	gcm2
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	606
Subcellular Localization	Nucleus .
Protein Description	Transcription factor with a minor role promoting glial cell differentiation and a more significant role in hematocyte differentiation. Gcm2, together with gcm, is required for the proliferation of plasmatocyte precursors, the expression of Croquemort protein, and the ability of plasmatocytes to convert into macrophages..
Protein Sequence	MVVINGYSFKTQQLLTQQPDHSQLTQFVQPQSQSTHSVHPGPSPGQQQAGGSMTMPSSSTGKGKREWDINDAIVPHVPDQEFDEFNEWSDGHVRHIYSLHNEEAKKHISGWAMRNTNNHNVNILKKSCLGVLVCSQHCTLPNGSKINLRPAICDKARRKQEGKACPNKSCRGGRLEIKPCRGHCGYPVTHFWRHSGNAIFFQAKGVHDHLRPDPKNSSVSKRAFGRVPLAGKSANGSVAKKSVIAGLVKQAKQQHSLISKVLKRPAVSNPLAHTALDIYQYNACGKCAGYSHCTCSYLDDSTTARSHQLSQSSNYGTNSWPLSGSESSAPCETAANVFTVNHQHITYNYPIYHATPAAATAAPSKSPSLPYACSISELAAYQQSSSGNSFAMGVPVHGHTQCQAVAYDSSPQLATPEPEFINYSQIKHLGGGGGQEEISCKAEPGPTIKYNATVETQPYVEDNYDYYYSPKAEYEMQQHHHQQQQSHQQFGGNQTAGHHYYESSSGYNGVSYFDTGTTTAPGNTATGNGLEVGYGGYYDHYTSYEQQMAVAGGFATAGGSTAPTVAAPPGHPPPPPPPPTLTYHHHHHHHLHHPAAATGLAPSVTH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of GCM2_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GCM2_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GCM2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GCM2_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
SEM2A_DROME	Sema-2a	physical	14605208
AT5F1_DROME	ATPsyn-b	physical	14605208

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GCM2_DROME

Related Literatures of Post-Translational Modification