GBS76_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GBS76_DROME
• UniProt AC: Q9VVY3
• Protein Name: Glycogen-binding subunit 76A
• Gene Name: Gbs-76A
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 681
• Protein Sequence: MNDPGDIPLTHTSTPDSRPPCSIISIIPTIGMSSCRGRAEAFARSLSSKLRTLGSQTTEEGEGNAEDEPIINGTSTNTWVNSHDSEQTVTDLQPLRHESDSFFDFDCELESPGSPVDECEYLRLIETASNTPHNSTAESGYACASMASSHSSSNDGPYFDASASTSTAAAAQDQTLPASEHKEYVNTLQLNGKHGLANGVQEEQPAFQDDVQEDEAFLQAQILNELQKHSNSLTEVEQTKPEEGKLTNGHLEKVEELELKDVLEVAGTTNRAPKVIAAPQEVEAFADRSQEQSPNDRVQKESSQERVPEGTPFEGVQGESPSDRVQTDASDERVQEEISNDTVQVESNHKSATESISTEVTTLERSPEESRNDELSPDSGVDETDKSASNLTVDVDLAQIEQAKQDATEAVEKSGAPSRGTTVDTTDDEDDCRPQRIRRCSSLKTGKTPPGTPGRKKIVRFADVLGLDLADVKTFLDEIPTIPKSAFEDLEILESEPPLQLGPKSDKLLMPLFQQPGGLPKFLDAVREKQVSLENAAVTDNINQTISGSVRVRNLDFHKSVHIRYSLDGWRSYADLQANYVENSCDGFSDIFTFVLFGNSLHVGQRLEFAVRFQCKGQQFWDNNYGANYCFQCLPSSTHTAGGSTASPPSVATGAVSTGHSASLVGLLSPTAGDAWCSSFY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
425	Phosphorylation	SRGTTVDTTDDEDDC CCCCCCCCCCCCCCC	27.99	25749252
426	Phosphorylation	RGTTVDTTDDEDDCR CCCCCCCCCCCCCCC	36.67	28490779
545	Phosphorylation	VTDNINQTISGSVRV ECCCCCCCCCCEEEE	16.78	17372656
547	Phosphorylation	DNINQTISGSVRVRN CCCCCCCCCEEEEEE	28.53	17372656
549	Phosphorylation	INQTISGSVRVRNLD CCCCCCCEEEEEECC	10.44	17372656

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GBS76_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GBS76_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GBS76_DROME !!

Protein-Protein Interaction

Oops, there are no PPI records of GBS76_DROME !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"An integrated chemical, mass spectrometric and computational strategyfor (quantitative) phosphoproteomics: application to Drosophilamelanogaster Kc167 cells.";
Bodenmiller B., Mueller L.N., Pedrioli P.G.A., Pflieger D.,Juenger M.A., Eng J.K., Aebersold R., Tao W.A.;
Mol. Biosyst. 3:275-286(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-545; SER-547 ANDSER-549, AND MASS SPECTROMETRY.
PubMed: 17372656