GATA2_MOUSE - dbPTM
GATA2_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GATA2_MOUSE
UniProt AC O09100
Protein Name Endothelial transcription factor GATA-2
Gene Name Gata2
Organism Mus musculus (Mouse).
Sequence Length 480
Subcellular Localization Nucleus.
Protein Description Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'..
Protein Sequence MEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHSPWTVSPFSKTPLHPSAAGAPGGPLSVYPGAAGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGGSVARGEDKDGVKYQVSLSESMKMEGGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYGSSLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSSKSKKSKKGAECFEELSKCMQEKSPPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
71PhosphorylationAHARARVSYSPAHAR
HHHHCCEECCCCHHH		17.8428066266
72PhosphorylationHARARVSYSPAHARL
HHHCCEECCCCHHHC		18.8028066266
73PhosphorylationARARVSYSPAHARLT
HHCCEECCCCHHHCC		14.2226745281
86MethylationLTGGQMCRPHLLHSP
CCCCCCCCCHHCCCC		19.14-
86Asymmetric dimethylarginineLTGGQMCRPHLLHSP
CCCCCCCCCHHCCCC		19.14-
182PhosphorylationPTPPKEVSPDPSTTG
CCCCCCCCCCCCCCC		25.3628066266
186PhosphorylationKEVSPDPSTTGAASP
CCCCCCCCCCCCCCC		46.0828066266
187PhosphorylationEVSPDPSTTGAASPA
CCCCCCCCCCCCCCC		34.3428066266
188PhosphorylationVSPDPSTTGAASPAS
CCCCCCCCCCCCCCC		29.2128066266
192PhosphorylationPSTTGAASPASSSAG
CCCCCCCCCCCCCCC		22.0625619855
195PhosphorylationTGAASPASSSAGGSV
CCCCCCCCCCCCCCC		28.3628066266
196PhosphorylationGAASPASSSAGGSVA
CCCCCCCCCCCCCCC		26.7228066266
197PhosphorylationAASPASSSAGGSVAR
CCCCCCCCCCCCCCC		28.5628066266
201PhosphorylationASSSAGGSVARGEDK
CCCCCCCCCCCCCCC		16.2228066266
288PhosphorylationKQRSKARSCSEGREC
HHHHHCCCCCCCCCC		27.1926745281
290PhosphorylationRSKARSCSEGRECVN
HHHCCCCCCCCCCCC		44.3126745281
324AcetylationNACGLYHKMNGQNRP
HHHHCHHHHCCCCCC		22.0910207073
340PhosphorylationIKPKRRLSAARRAGT
CCHHHHHHHHHHHCC		20.33-
390AcetylationNRPLTMKKEGIQTRN
CCCCCHHHHHHHHHH		50.8015611575
401PhosphorylationQTRNRKMSSKSKKSK
HHHHHHCCCCCHHHH		37.3322817900
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GATA2_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GATA2_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GATA2_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GATA2_MOUSE

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Related Literatures of Post-Translational Modification

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