GALK1_MOUSE - dbPTM
GALK1_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID GALK1_MOUSE
UniProt AC Q9R0N0
Protein Name Galactokinase
Gene Name Galk1
Organism Mus musculus (Mouse).
Sequence Length 392
Subcellular Localization
Protein Description Major enzyme for galactose metabolism..
Protein Sequence MAAWRPPRVEELLAEARRAFMEEFGAEPELAVSAPGRVNLIGEHTDYNQGLVLPMALELVTVMVGSPRTDGLVSLLTTSKDADEPQRLQFPLPSAQWSLEPGIPQWANYVKGVIQHYPASPLVGFSAVVVSSVPLGGGLSSSASLEVATYTFIQQLCPDSGAIAARAQVCQRAEHSFAGVPCGIMDQLIALLGQKGYALLIDCRSLETSLVPLSDPKLAVLITNSNVRHSLGSSEYPVRRRQCEEVAQALGKESLREVRMEELEAGRELMSKEGFRRARHVVSEIRRTAQAAAAMSRGDYKAFGRLMVESHYSLRDDYEVSCPELDQLVEAALSVPGVYGSRMTGGGFGGCTVTLLEASVAPLVIDHIQEQYSGTATFYLSQAADGAQVLSL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
80AcetylationVSLLTTSKDADEPQR
HHHEECCCCCCCCCC		60.0523954790
80UbiquitinationVSLLTTSKDADEPQR
HHHEECCCCCCCCCC		60.05-
80SuccinylationVSLLTTSKDADEPQR
HHHEECCCCCCCCCC		60.0523954790
217AcetylationLVPLSDPKLAVLITN
EEECCCCCEEEEEEC		4.9223954790
217UbiquitinationLVPLSDPKLAVLITN
EEECCCCCEEEEEEC		4.92-
217UbiquitinationLVPLSDPKLAVLITN
EEECCCCCEEEEEEC		4.92-
223O-linked_GlycosylationPKLAVLITNSNVRHS
CCEEEEEECCCHHHC		25.2930059200
230PhosphorylationTNSNVRHSLGSSEYP
ECCCHHHCCCCCCCC		6.7022817900
233PhosphorylationNVRHSLGSSEYPVRR
CHHHCCCCCCCCCCH		39.0728066266
234PhosphorylationVRHSLGSSEYPVRRR
HHHCCCCCCCCCCHH		56.4028066266
272AcetylationAGRELMSKEGFRRAR
HHHHHHHHHHHHHHH		57.1522826441
272AcetylationAGRELMSKEGFRRAR
HHHHHHHHHHHHHHH		57.15-
272MalonylationAGRELMSKEGFRRAR
HHHHHHHHHHHHHHH		57.1526320211
301MalonylationAMSRGDYKAFGRLMV
HHHCCCHHHHHHHHH		13.0926320211
301SuccinylationAMSRGDYKAFGRLMV
HHHCCCHHHHHHHHH		13.0923954790
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of GALK1_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of GALK1_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of GALK1_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of GALK1_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of GALK1_MOUSE

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Related Literatures of Post-Translational Modification

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