GA2L3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GA2L3_MOUSE
• UniProt AC: Q3UWW6
• Protein Name: GAS2-like protein 3
• Gene Name: Gas2l3
• Organism: Mus musculus (Mouse).
• Sequence Length: 683
• Subcellular Localization: Cytoplasm. Cytoplasm, cytoskeleton. Localizes to microtubule and actin cytoskeletons..
• Protein Description: Cytoskeletal linker protein. May promote and stabilize the formation of the actin and microtubule network (By similarity)..
• Protein Sequence: MTMQPAIQVWFGEDLPLSPRCPLTPRHGPGLADVCQYDEWIAVRHEATLLPMQEDLSIWLSGLLGVDIKAERLLEELDNGVLLCQLINVLQNMVKGCHSDEPGNFPMRKVPCKKDAASGSFFARDNTANFLHWCRHIGVDETYLFESEGLVLHKDPRQVYLCLLEIGRIVSRYGVEPPVLVKLEKEIELEETLLNASGLEESISIPKSCCQQEELHEAVKHIAEDPPCSCSHRFSIEYLSEGRYRLGEKILFIRMLHGKHVMVRVGGGWDTLQGFLLKYDPCRILQFATLEQKILAFQKGVSNESVPDSPARTPKPPEMNPLSAVNMFQKQNLRPGTPVSVPKNKEKQVRLPGARLPASSVKGNLASPSTRAKRPDSPASFPHPKVTSLKDAAKKTTAPSNSVSQSLASPNPGSKPSTAQCASESSRKCVTFPKTAQTKAIPAQNSRDLSKSRLLPSKSPGKMEPKHLKHNHLSSRDESRINLSSKSPKLPKGAMHGRPNPSPFQPPAKVTKPSSKTGAIGLGTQSQPPTRTPRSGAVSAQRLQSTLNLNSPASVCSGSSAKATQGSKGKNTVSVAKKQPQSKGVCRNPGPGSSKSPGRTPLSIVTVPQSATKTETVSKSAKTAMKGQYSAKGPPKSSKPPTSFRDPPSSGKGADSGDKMPTARKKEEDDHYFVMTGNKKLRK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
235	Phosphorylation	CSCSHRFSIEYLSEG CCCCCCEEEEEHHHC	17.92	28066266
309	Phosphorylation	SNESVPDSPARTPKP CCCCCCCCCCCCCCC	17.87	30482847
337	Phosphorylation	KQNLRPGTPVSVPKN HCCCCCCCCCCCCCC	24.17	28066266
340	Phosphorylation	LRPGTPVSVPKNKEK CCCCCCCCCCCCCCC	33.63	28066266
367	Phosphorylation	SVKGNLASPSTRAKR HHCCCCCCCCCCCCC	23.66	28066266
369	Phosphorylation	KGNLASPSTRAKRPD CCCCCCCCCCCCCCC	28.20	28066266
370	Phosphorylation	GNLASPSTRAKRPDS CCCCCCCCCCCCCCC	37.72	28066266
377	Phosphorylation	TRAKRPDSPASFPHP CCCCCCCCCCCCCCC	25.66	27600695
380	Phosphorylation	KRPDSPASFPHPKVT CCCCCCCCCCCCCCC	42.57	29550500
435	Phosphorylation	KCVTFPKTAQTKAIP CCCCCCCCCCCCCCC	25.00	-
466	Ubiquitination	SPGKMEPKHLKHNHL CCCCCCCCHHCCCCC	48.54	-
487	Phosphorylation	RINLSSKSPKLPKGA HHCCCCCCCCCCCCC	29.25	25338131
545	Phosphorylation	VSAQRLQSTLNLNSP CCHHHHHHHHCCCCC	39.18	23140645
546	Phosphorylation	SAQRLQSTLNLNSPA CHHHHHHHHCCCCCC	13.50	23140645
551	Phosphorylation	QSTLNLNSPASVCSG HHHHCCCCCCHHHCC	25.63	23140645
554	Phosphorylation	LNLNSPASVCSGSSA HCCCCCCHHHCCCCC	27.34	23140645
557	Phosphorylation	NSPASVCSGSSAKAT CCCCHHHCCCCCCCC	39.28	23140645
559	Phosphorylation	PASVCSGSSAKATQG CCHHHCCCCCCCCCC	15.72	-
603	Phosphorylation	SPGRTPLSIVTVPQS CCCCCCCEEEECCCC	19.06	22871156
614	Phosphorylation	VPQSATKTETVSKSA CCCCCCCCEECCHHH	32.31	-
616	Phosphorylation	QSATKTETVSKSAKT CCCCCCEECCHHHHH	35.00	-
632	Acetylation	MKGQYSAKGPPKSSK HCCCCCCCCCCCCCC	67.04	19844955
662	Phosphorylation	DSGDKMPTARKKEED CCCCCCCCCCCCCCC	35.28	28576409

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GA2L3_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GA2L3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GA2L3_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of GA2L3_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.