GA2L2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GA2L2_HUMAN
• UniProt AC: Q8NHY3
• Protein Name: GAS2-like protein 2
• Gene Name: GAS2L2
• Organism: Homo sapiens (Human).
• Sequence Length: 880
• Subcellular Localization: Cytoplasm, cytoskeleton .
• Protein Description: Seems to be involved in the cross-linking of microtubules and microfilaments..
• Protein Sequence: MSQPAGGRRKPRTLGPPVCSIRPFKSSEQYLEAMKEDLAEWLRDLYGLDIDAANFLQVLETGLVLCQHANVVTDAALAFLAEAPAQAQKIPMPRVGVSCNGAAQPGTFQARDNVSNFIQWCRKEMGIQEVLMFETEDLVLRKNVKNVVLCLLELGRRAWRFGVAAPTLVQLEEEIEEEVRRELALPPPDPSPPAPPRRQPCHFRNLDQMVQSLVSHCTCPVQFSMVKVSEGKYRVGDSNTLIFIRILRNHVMVRVGGGWDTLGHYLDKHDPCRCTSLSHKPGSFLKPPAPPVQHEVRVQDGPSQTQPTMTISRSQSPPPPVDWKTYTSSDRRLRPPTPSSPRPRRERGAGTGASREMAPFLRCQERSLIPSWRQPTAGDSPPSPQSSSTQKGRDPQCTSSGKREERYPPELPRGRIPTSWVHEETDSWGTDAGNPTPQRLRAIEATTKGISARGPSPLPRSFGPAECLGLRLPLRDEAKGAFFQFREPESVRSPTPVQGLTKIPIRLPPARPPTPGRSFPGATSGSPRTELGRDPIPLRAVTVDLAGSTHGDCSVEVRQEDQQLDIQVMAEARESWDLGLQEQEGRYTPLPLGGNKEQAIYCSLEEEILGNMKLLEVRSACPQGTRSGVIPRSGVYIPRLAGQWPEPGGPYDKAIQELAQGSPSLLKVDLEAWKAAPTGSPKPAVTPGPGSLKGKLGARQSGPRTKASLSAKGTHMRKVPPQGGQDCSASTVSASPEAPTPSPLDPNSDKAKACLSKGRRTLRKPKRVPSIYKLKLRPRIRPRRDHRPEKQPSRIPRPLAYVFLGPARQPPKDRLLRAVLGSKGGEASRVDGASVGEEEEEGKEEKEPAAPLESSPQPPEGLQPHWLNQAPLPPEEESWV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
13	Phosphorylation	GGRRKPRTLGPPVCS CCCCCCCCCCCCCCC	44.59	22817900
26	Phosphorylation	CSIRPFKSSEQYLEA CCCCCCCCHHHHHHH	39.21	-
191	Phosphorylation	ALPPPDPSPPAPPRR CCCCCCCCCCCCCCC	51.39	28787133
265	Phosphorylation	GWDTLGHYLDKHDPC CHHHHHHHHHCCCCC	18.13	-
283	Phosphorylation	SLSHKPGSFLKPPAP CCCCCCCCCCCCCCC	35.61	24719451
303	Phosphorylation	VRVQDGPSQTQPTMT EECCCCCCCCCCEEE	51.92	30631047
316	Phosphorylation	MTISRSQSPPPPVDW EEEECCCCCCCCCCC	40.39	30087585
337	Phosphorylation	DRRLRPPTPSSPRPR CCCCCCCCCCCCCCC	38.19	23312004
339	Phosphorylation	RLRPPTPSSPRPRRE CCCCCCCCCCCCCCC	56.29	23312004
340	Phosphorylation	LRPPTPSSPRPRRER CCCCCCCCCCCCCCC	26.57	23312004
371	Phosphorylation	QERSLIPSWRQPTAG HHCCCCCCCCCCCCC	28.09	26091039
376	Phosphorylation	IPSWRQPTAGDSPPS CCCCCCCCCCCCCCC	34.63	30576142
380	Phosphorylation	RQPTAGDSPPSPQSS CCCCCCCCCCCCCCC	37.48	30576142
398	Phosphorylation	KGRDPQCTSSGKREE CCCCCCCCCCCCCCC	22.23	30576142
451	Phosphorylation	EATTKGISARGPSPL HHHCCCHHHCCCCCC	22.15	27174698
456	Phosphorylation	GISARGPSPLPRSFG CHHHCCCCCCCCCCC	41.72	24719451
460	Methylation	RGPSPLPRSFGPAEC CCCCCCCCCCCHHHH	52.91	-
471	Methylation	PAECLGLRLPLRDEA HHHHHCEECCCCCHH	32.25	-
501	Phosphorylation	PTPVQGLTKIPIRLP CCCCCCCCCCCCCCC	33.48	-
526	Phosphorylation	FPGATSGSPRTELGR CCCCCCCCCCCCCCC	15.81	27251275
633	Phosphorylation	RSGVIPRSGVYIPRL CCCCCCCCCCCCCCC	27.53	24719451
636	Phosphorylation	VIPRSGVYIPRLAGQ CCCCCCCCCCCCCCC	14.56	24719451
664	Phosphorylation	ELAQGSPSLLKVDLE HHHCCCCCCEEEEHH	48.29	24719451
678	Phosphorylation	EAWKAAPTGSPKPAV HHHHCCCCCCCCCCC	45.63	27251275
680	Phosphorylation	WKAAPTGSPKPAVTP HHCCCCCCCCCCCCC	32.03	27251275
693	Ubiquitination	TPGPGSLKGKLGARQ CCCCCCCCHHCCCCC	56.55	-
708	Phosphorylation	SGPRTKASLSAKGTH CCCCCCEECCCCCCC	25.14	23312004
770	Phosphorylation	RKPKRVPSIYKLKLR CCCCCCCCEEECEEC	35.38	27966365
793	Phosphorylation	HRPEKQPSRIPRPLA CCCCCCCCCCCCCCE	40.11	17081983
801	Phosphorylation	RIPRPLAYVFLGPAR CCCCCCEEEECCCCC	10.22	22817900
822	Phosphorylation	LLRAVLGSKGGEASR HHHHHHCCCCCCHHC	24.78	-
855	Phosphorylation	PAAPLESSPQPPEGL CCCCCCCCCCCCCCC	20.41	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GA2L2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GA2L2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GA2L2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of GA2L2_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.