dbPTM

FUM1_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	FUM1_ARATH
UniProt AC	P93033
Protein Name	Fumarate hydratase 1, mitochondrial
Gene Name	FUM1
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	492
Subcellular Localization	Mitochondrion .
Protein Description
Protein Sequence	MSIYVASRRLSGGTTVTALRYATSLRSYSTSFREERDTFGPIQVPSDKLWGAQTQRSLQNFEIGGERERMPEPIVRAFGVLKKCAAKVNMEYGLDPTIGKAIMQAAQEVAEGKLNDHFPLVVWQTGSGTQSNMNANEVIANRAAEILGRKRGEKCVHPNDHVNRSQSSNDTFPTVMHIAAATEINSRLIPSLKTLHSTLESKSFEFKDIVKIGRTHTQDATPLTLGQEFGGYATQVKYGLNRVTCTLPRLYQLAQGGTAVGTGLNTKKGFDVKIAAAVAEETNLPFVTAENKFEALAAHDACVETSGSLNTIATSLMKIANDIRFLGSGPRCGLGELVLPENEPGSSIMPGKVNPTQCEALTMVCAQVMGNHVAVTVGGSNGHFELNVFKPVIASALLHSVRLIADASASFEKNCVRGIEANRERISKLLHESLMLVTSLNPKIGYDNAAAVAKKAHKEGCTLKEAALNLGVLTAEEFDTLVVPEKMIGPSD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
103	Sulfoxidation	PTIGKAIMQAAQEVA HHHHHHHHHHHHHHH	2.37	23289948
193	Acetylation	SRLIPSLKTLHSTLE HHHHCHHHHHHHHHH	54.07	24727099
201	Phosphorylation	TLHSTLESKSFEFKD HHHHHHHCCCEEHHH	36.39	25561503
203	Phosphorylation	HSTLESKSFEFKDIV HHHHHCCCEEHHHHE	39.01	25561503
207	Acetylation	ESKSFEFKDIVKIGR HCCCEEHHHHEEECC	39.07	24727099
266	Phosphorylation	AVGTGLNTKKGFDVK EEECCCCCCCCCCCH	38.89	29654922
267	Acetylation	VGTGLNTKKGFDVKI EECCCCCCCCCCCHH	50.23	24727099

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of FUM1_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of FUM1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of FUM1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of FUM1_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of FUM1_ARATH

Related Literatures of Post-Translational Modification