FRIH_HORSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FRIH_HORSE
• UniProt AC: Q8MIP0
• Protein Name: Ferritin heavy chain
• Gene Name: FTH1
• Organism: Equus caballus (Horse).
• Sequence Length: 182
• Protein Description: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity)..
• Protein Sequence: MTTAFPSQVRQNYHQDSEAAINRQINLELHASYVYLSMSFYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDQDDWENGLKAMECALHLEKNVNESLLELHKLATDKNDPHLCDFLETHYLNEQVKAIKELGDHVTNLRRMGAPESGMAEYLFDKHTLGECDES

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MTTAFPSQ -------CCCCCHHH	7.29	-
2	Acetylation	------MTTAFPSQV ------CCCCCHHHH	27.17	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FRIH_HORSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FRIH_HORSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FRIH_HORSE !!

Protein-Protein Interaction

Oops, there are no PPI records of FRIH_HORSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.