dbPTM

FOXE3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	FOXE3_MOUSE
UniProt AC	Q9QY14
Protein Name	Forkhead box protein E3
Gene Name	Foxe3
Organism	Mus musculus (Mouse).
Sequence Length	288
Subcellular Localization	Nucleus .
Protein Description	Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle. [PubMed: 10652278]
Protein Sequence	MDAQVAFSGFPALPSLTPSGPQLPTLAGAEPGREPEEVVGGGDAEPTAVPGPGKRRRRPLQRGKPPYSYIALIAMALAHAPGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNPGKGNYWTLDPAAADMFDNGSFLRRRKRFKRAELPAPPPPPPPFPYAPFPPPPAPASAPPARLFRLDSLLGLQPEPPGPVAPEPPCCAAPDAAFPPCAAAASPPLYSPASERLGLPAPLPAQPLLALAGSAGALGPLGAGEAYLRQPGFAPGLERYL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
261	Phosphorylation	PLLALAGSAGALGPL HHHHHHCCCCCCCCC	20.23	29899451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of FOXE3_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of FOXE3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of FOXE3_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
SALL4_MOUSE	Sall4	physical	20211142

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of FOXE3_MOUSE

Related Literatures of Post-Translational Modification