FM1AA_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FM1AA_MOUSE
• UniProt AC: Q9Z2G1
• Protein Name: Protein fem-1 homolog A-A
• Gene Name: Fem1aa
• Organism: Mus musculus (Mouse).
• Sequence Length: 654
• Subcellular Localization: Cytoplasm.
• Protein Description: Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4 (By similarity)..
• Protein Sequence: MDLHTAVYNAAHDGKLPLLQKLLAGRGREELEELLGEVAGGGTPLLIAARRGHLDVVEYLVDHCGASVEASGSVHFDGETIEGAPPLWAASAAGHLAVVRSLLRRGASVNRTTRTNSTPLRAACFDGHLDVVRYLVGEHKADLEVANRHGHTCLMISCYKGHREIARYLLERGAQVNRRSAKGNTALHDCAESGSLEILQLLLGCHARMERDGYGMTPLLAASVTGHTNIVEYLIQEQPGHEQLSGTELPGEGSSQVAGNHCSTPEEAEPYESCCPTSREAAVEALELLGATYVDKKRDLLGALKHWRRAMELRHQGGGYLPKPEPQQLVLAYDYSREVTTPQELEALITDPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCIRLWKYALDMQQNNLEPLSPMTASSFLSFAELFSYVLQDRSAKGNLGMQLGFADLMGVLSKGVREVERALQLPKEPGDSAQFTKAIAIILHLLYLLEKVECTPSQEHLKHQTVYRLLKCAPRGKNGFTPLHMAVDKETTNVGRYRVGVFPSLQVVKVLLDCGADPDSRDFDNNTPLHIAAQNNCPAIMDALIEAGAHMDATNAFKKTAYELLDSKLLAKSTVQPFNYVTLQCLAARALDRNKVPYKGFIPEELEAFIQLH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MDLHTAVYNAAH ---CCHHHHHHHHHH	25.72	-
8	Phosphorylation	MDLHTAVYNAAHDGK CCHHHHHHHHHHCCC	9.16	-
15	Ubiquitination	YNAAHDGKLPLLQKL HHHHHCCCCHHHHHH	53.65	22790023
296	Ubiquitination	LGATYVDKKRDLLGA HCCCCCCHHHHHHHH	39.40	22790023
608	Phosphorylation	TAYELLDSKLLAKST HHHHHHCCHHHHCCC	25.77	-
609	Ubiquitination	AYELLDSKLLAKSTV HHHHHCCHHHHCCCC	47.38	22790023

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FM1AA_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FM1AA_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FM1AA_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NFKB1_MOUSE	Nfkb1	physical	18270204

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.