dbPTM

FLVC2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	FLVC2_MOUSE
UniProt AC	Q91X85
Protein Name	Feline leukemia virus subgroup C receptor-related protein 2
Gene Name	Flvcr2
Organism	Mus musculus (Mouse).
Sequence Length	551
Subcellular Localization	Cell membrane Multi-pass membrane protein.
Protein Description	Acts as an importer of heme. Also acts as a transporter for a calcium-chelator complex, important for growth and calcium metabolism (By similarity)..
Protein Sequence	MVNESLNQEESNDRPAPESEFQMDTSYSTQPSGSIHPSVSGHPSVSGHPSVSGHPSVSIHPSVSIDPSVSVRPSSSALPSTLAQPSGLTHHSSLVREDSVIKVSKRRWVVVLVFSCYSLCNAFQWIQYGSINNIFMNFYGVSAFAIDWLSMCYMLTYIPLLLPVAWMLEKFGLRTIAITGSALNCLGAWVKLGSLEPHLFPVTMVGQVICSVAQVFILGMPSRIASVWFGADEVSTACSVAVFGNQLGIAIGFLVPPVLVPNIKDPEKLAYHISIMFYIIGGVATFLFILVIIVFKEKPKHPPSRAQSLSYALATTDASYLSSIVRLFKNLNFVLLVITYGLNAGAFYALSTLLNRMVILHFPGEEVNAGRIGLTIVIAGMFGAMISGIWLDKSKTYKETTLVVYIMTLVGMVVYTFTLNLNHLWIVFITAGTLGFFMTGYLPLGFEFAVEFTYPESEGVSSGLLNVSAQVFGIVFTISQGQIIDNHGTMFGNIFLCVFLALGSALTAFIKSDLRRQRANKDAPETKVQEEEEEEEGSNTSKVPVVSEAHL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
80	Phosphorylation	PSSSALPSTLAQPSG CCCCCCCCCCCCCCC	36.58	25293948
81	Phosphorylation	SSSALPSTLAQPSGL CCCCCCCCCCCCCCC	24.95	25293948
86	Phosphorylation	PSTLAQPSGLTHHSS CCCCCCCCCCCCCHH	34.06	19060867
89	Phosphorylation	LAQPSGLTHHSSLVR CCCCCCCCCCHHHCC	22.52	25293948
92	Phosphorylation	PSGLTHHSSLVREDS CCCCCCCHHHCCCCC	20.12	25293948
93	Phosphorylation	SGLTHHSSLVREDSV CCCCCCHHHCCCCCE	26.91	25293948
348	Phosphorylation	GLNAGAFYALSTLLN CCCHHHHHHHHHHHH	13.19	-
538	Phosphorylation	EEEEEEGSNTSKVPV HHHHHCCCCCCCCCC	39.97	19060867
540	Phosphorylation	EEEEGSNTSKVPVVS HHHCCCCCCCCCCCE	31.46	19060867
541	Phosphorylation	EEEGSNTSKVPVVSE HHCCCCCCCCCCCEE	35.59	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of FLVC2_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of FLVC2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of FLVC2_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of FLVC2_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of FLVC2_MOUSE

Related Literatures of Post-Translational Modification