dbPTM

FIMB1_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	FIMB1_ARATH
UniProt AC	Q7G188
Protein Name	Fimbrin-1 {ECO:0000303\|PubMed:11123801}
Gene Name	FIM1 {ECO:0000303\|PubMed:11123801}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	687
Subcellular Localization	Cytoplasm, cytoskeleton .
Protein Description	Cross-links actin filaments (F-actin) in a calcium independent manner. Induces the formation of actin aggregates. Stabilizes and prevents F-actin depolymerization mediated by profilin. Key regulator of actin cytoarchitecture, probably involved in cell cycle, cell division, cell elongation and cytoplasmic tractus..
Protein Sequence	MSGYVGVVVSDPWLQSQFTQVELRTLNSKYVSVKNQNGKVTIEDLPPLFAKLKALSATFKEDEIKGMLGELGSDTSTDVSFEEFLKIYLNLLSKAAEKSGGHHKNSSSFLKACTTTLLHTIYQSEKGPFVQHINRYLGDDPFLKQFLPLDPHSNQLYELVKDGVLLCKLINVAVPGTIDERAINTKRVLNPWERNENHTLCLNSAKAVGCSVVNIGTQDLAEGRPHLVLGLISQLIKIQVLADLNLKKTPQLVELLEDSDDVEELLRLPPEKVLLKWMNFHLKKGGYKKTVSNFSADLKDAQAYAFLLNVLAPEHCDPATLDAKDPLERAELVLSHAERMNCKRYLTAEEIVEGSSTLNLAFVAQIFHERNGLNKDGKYAFAEMMTEDVETCRDERCYRLWINSLGIDSYVNNVFEDVRNGWILLEVLDKVSPSSVNWKHASKPPIKMPFRKVENCNQVIKIGKQLKFSLVNVAGNDIVQGNKKLILGLLWQLMRFHMLQLLKSLRSRTLGKEMTDADILSWANRKVRTMGRKLQIESFKDKSLSSGLFFLNLLWAVEPRVVNWNLVTKGETDDEKRLNATYIVSVARKLGCSVFLLPEDIVEVNQKMILILTASIMYWSLQRHSRESSDSSSTQSTTTTCTSTASSPAPSVTEEEEVSSLSGEVTSLAVGDAVSEITTVSEEASIE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MSGYVGVVVSD ----CCCEEEEEECC	6.16	19880383
10	Phosphorylation	GYVGVVVSDPWLQSQ CEEEEEECCHHHHHC	26.75	19880383
581	Phosphorylation	DEKRLNATYIVSVAR CHHHCCHHHHHHHHH	16.83	28295753
582	Phosphorylation	EKRLNATYIVSVARK HHHCCHHHHHHHHHH	9.27	28295753

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of FIMB1_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of FIMB1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of FIMB1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of FIMB1_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of FIMB1_ARATH

Related Literatures of Post-Translational Modification