FH4_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FH4_ARATH
• UniProt AC: O48682
• Protein Name: Formin-like protein 4
• Gene Name: FH4
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 763
• Subcellular Localization: Cell membrane ; Single-pass membrane protein .
• Protein Description: Might be involved in the organization and polarity of the actin cytoskeleton..
• Protein Sequence: MAAMLMQPWPPFLPHLTLVFLTLILFFPNQSFSQSDSPRNIETFFPNDTITPPVQSPVLSPPQNPSSSSSDSDRGNILRAVLITAASTLLVAAVFFFLVHKCRRRRNRVGGVDNTLQPPVPPLAEAALAREGFTRFGGNVKGLILDENGLDVLYWRKLQQSQRDNKGGSFRKEIIHGDDEEKNVIYSKSKKKSGPVTETPLLRGRSSTSHSVIHNDNYRNATTTHPPHVKTDSFEFVKPDPTPPPPPPPPIPVKQSATPPPPPPPKLKNNGPSPPPPPPLKKTAALSSSASKKPPPAPRGSSSGESSNGQVKLKPLHWDKVNPDSDHSMVWDKIDRGSFSFDGDLMEALFGYVAVGKKSPDDGGDKKPSSASPAQIFILDPRKSQNTAIVLKSLGMTRDELVESLMEGHDFHPDTLERLSRIAPTKEEQSAILQFDGDTKMLADAESFLFHLLKAVPCAFTRLNALLFRANYYPEISNHNKNLQTLDLACTELRSRGLFVKLLEAILKSGNRMNAGTARGDAQAFNLTALLKLSDVKSVDGKTTLLNFVVEEVVRSEGKRCVLNRRTNRSFSRSSSSSISEVISKEEQEKEYLRLGLPVVGGLSSEFTNVKKAAAVDYDTVAATCLALTSRAKDARRVLAQSEGDNKEGVRFVKKMNEFLDSVEEEVKLAKEEEKKVLELVKRTTEYYQAGAVKGKNPLHLFVIVRDFLAMVDKVCVEIARNLQRRSSMGSTQQRNAVKFPVLPPNFMSDRSRSDSGGSDSDM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
231	Phosphorylation	THPPHVKTDSFEFVK CCCCCCCCCCCCCCC	35.47	17317660
287	Phosphorylation	LKKTAALSSSASKKP CCCHHHCCCCCCCCC	19.95	30407730
288	Phosphorylation	KKTAALSSSASKKPP CCHHHCCCCCCCCCC	30.67	30407730
289	Phosphorylation	KTAALSSSASKKPPP CHHHCCCCCCCCCCC	32.93	30407730
291	Phosphorylation	AALSSSASKKPPPAP HHCCCCCCCCCCCCC	43.06	30407730
687	Phosphorylation	LVKRTTEYYQAGAVK HHHHHHHHHHCCCCC	9.97	19880383
688	Phosphorylation	VKRTTEYYQAGAVKG HHHHHHHHHCCCCCC	5.90	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FH4_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FH4_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FH4_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of FH4_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.