FGF6_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FGF6_HUMAN
• UniProt AC: P10767
• Protein Name: Fibroblast growth factor 6
• Gene Name: FGF6
• Organism: Homo sapiens (Human).
• Sequence Length: 208
• Subcellular Localization: Secreted, extracellular space.
• Protein Description: Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration..
• Protein Sequence: MALGQKLFITMSRGAGRLQGTLWALVFLGILVGMVVPSPAGTRANNTLLDSRGWGTLLSRSRAGLAGEIAGVNWESGYLVGIKRQRRLYCNVGIGFHLQVLPDGRISGTHEENPYSLLEISTVERGVVSLFGVRSALFVAMNSKGRLYATPSFQEECKFRETLLPNNYNAYESDLYQGTYIALSKYGRVKRGSKVSPIMTVTHFLPRI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	LGQKLFITMSRGAGR CCCEEEEEECCCCHH	11.19	24719451
12	Phosphorylation	QKLFITMSRGAGRLQ CEEEEEECCCCHHHH	20.93	24719451
45	N-linked_Glycosylation	SPAGTRANNTLLDSR CCCCCCCCCEEECCC	38.43	UniProtKB CARBOHYD

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FGF6_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FGF6_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FGF6_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of FGF6_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.