FCSD2_MOUSE - dbPTM
FCSD2_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FCSD2_MOUSE
UniProt AC Q3USJ8
Protein Name F-BAR and double SH3 domains protein 2
Gene Name Fchsd2
Organism Mus musculus (Mouse).
Sequence Length 740
Subcellular Localization
Protein Description
Protein Sequence MQPPPRKVKVTQELRNIQGEQMTKLQAKHQAECDLLEDMRTFSQKKAAIEREYAQGIQKLASQYLKRDWPGIKTDDRNDYRSMYPVWKSFLEGTMQVAQSRINICENYKNFISEPARAVRSLKEQQLKRCVDQLTKIQTELQETVKDLVKGKKKYFETEQMAHAVREKADIEAKSKLSLFQSRISLQKASVKLKARRSECNTKATHARNDYLLTLAAANAHQDRYYQTDLVNIMKALDGNVYDHLKDYLIAFSRTELETCQAIQNTFQFLLENSSKVVRDYNLQLFLQENAVFHKPQPFQFQPCDSDTSRQLESETGTTEEHSLNKEARKWATRVAREHKNIVHQQRVLNELECHGVALSEQSRAELEQKIDEARESIRKAEIIKLKAEARLDLLKQIGVSVDTWLKSAMNQVMEELENERWARPPAVTSNGTLHSLNADAEREEGEEFEDNMDVFDDSSSSPSGTLRNYPLTCKVVYSYKASQPDELTIEEHEVLEVIEDGDMEDWVKARNKVGQVGYVPEKYLQFPTSNSLLSMLQSLAALDSRSHTSSNSTEAELVSGSLNGDASVCFVKALYDYEGQTDDELSFPEGAIIRILNKENQDDDGFWEGEFSGRIGVFPSVLVEELSASENGDTPWTREIQISPSPKPHTSLPPLPLYDQPPSSPYPSPDKRSSQFFPRSPSANENSLHAESPGFSQASRQTPDTSYGKLRPVRAAPPPPTQNHRRTTEKMEDVEITLV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
182PhosphorylationSKLSLFQSRISLQKA
HHHHHHHHHHHHHHH		25.0123984901
185PhosphorylationSLFQSRISLQKASVK
HHHHHHHHHHHHHHH		24.5223984901
190PhosphorylationRISLQKASVKLKARR
HHHHHHHHHHHHHHH		27.1625266776
283 (in isoform 3)Phosphorylation-3.6829899451
286 (in isoform 3)Phosphorylation-4.2220415495
314O-linked_GlycosylationDTSRQLESETGTTEE
CCCHHHHCCCCCCCH		49.3930016717
316O-linked_GlycosylationSRQLESETGTTEEHS
CHHHHCCCCCCCHHH		49.4630016717
318O-linked_GlycosylationQLESETGTTEEHSLN
HHHCCCCCCCHHHCC		38.1530016717
319O-linked_GlycosylationLESETGTTEEHSLNK
HHCCCCCCCHHHCCH		40.4930016717
321 (in isoform 2)Phosphorylation-36.3629899451
324 (in isoform 2)Phosphorylation-13.1620415495
644PhosphorylationWTREIQISPSPKPHT
CEEEEEECCCCCCCC		11.7126824392
646PhosphorylationREIQISPSPKPHTSL
EEEEECCCCCCCCCC		38.4722499769
651PhosphorylationSPSPKPHTSLPPLPL
CCCCCCCCCCCCCCC		40.2522499769
652PhosphorylationPSPKPHTSLPPLPLY
CCCCCCCCCCCCCCC		35.5322499769
659PhosphorylationSLPPLPLYDQPPSSP
CCCCCCCCCCCCCCC		15.5922499769
664PhosphorylationPLYDQPPSSPYPSPD
CCCCCCCCCCCCCCC		51.1022499769
665PhosphorylationLYDQPPSSPYPSPDK
CCCCCCCCCCCCCCC		33.9422499769
667PhosphorylationDQPPSSPYPSPDKRS
CCCCCCCCCCCCCCC		20.4922499769
669PhosphorylationPPSSPYPSPDKRSSQ
CCCCCCCCCCCCCCC		39.6322499769
674PhosphorylationYPSPDKRSSQFFPRS
CCCCCCCCCCCCCCC		33.9425619855
675PhosphorylationPSPDKRSSQFFPRSP
CCCCCCCCCCCCCCC		34.7326824392
681PhosphorylationSSQFFPRSPSANENS
CCCCCCCCCCCCCCC		24.3626824392
683PhosphorylationQFFPRSPSANENSLH
CCCCCCCCCCCCCCC		45.0027742792
688PhosphorylationSPSANENSLHAESPG
CCCCCCCCCCCCCCC		18.4925619855
693PhosphorylationENSLHAESPGFSQAS
CCCCCCCCCCCCHHC		30.9825619855
697PhosphorylationHAESPGFSQASRQTP
CCCCCCCCHHCCCCC		30.6525619855
700PhosphorylationSPGFSQASRQTPDTS
CCCCCHHCCCCCCCC		19.7928066266
708PhosphorylationRQTPDTSYGKLRPVR
CCCCCCCCCCCCCCC		22.0029514104
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FCSD2_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FCSD2_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FCSD2_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of FCSD2_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FCSD2_MOUSE

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Large-scale phosphorylation analysis of mouse liver.";
Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-683, AND MASSSPECTROMETRY.

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