| UniProt ID | FBCD1_HUMAN | |
|---|---|---|
| UniProt AC | Q8N539 | |
| Protein Name | Fibrinogen C domain-containing protein 1 | |
| Gene Name | FIBCD1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 461 | |
| Subcellular Localization |
Membrane Single-pass type II membrane protein . |
|
| Protein Description | Acetyl group-binding receptor which shows a high-affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components.. | |
| Protein Sequence | MVNDRWKTMGGAAQLEDRPRDKPQRPSCGYVLCTVLLALAVLLAVAVTGAVLFLNHAHAPGTAPPPVVSTGAASANSALVTVERADSSHLSILIDPRCPDLTDSFARLESAQASVLQALTEHQAQPRLVGDQEQELLDTLADQLPRLLARASELQTECMGLRKGHGTLGQGLSALQSEQGRLIQLLSESQGHMAHLVNSVSDILDALQRDRGLGRPRNKADLQRAPARGTRPRGCATGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 152 | Phosphorylation | PRLLARASELQTECM HHHHHHHHHHHHHHC | 33.03 | - | |
| 164 (in isoform 2) | Phosphorylation | - | 20.30 | 22210691 | |
| 166 (in isoform 2) | Phosphorylation | - | 31.16 | 22210691 | |
| 167 | Phosphorylation | GLRKGHGTLGQGLSA CCCCCCCCCHHHHHH | 23.26 | - | |
| 173 | Phosphorylation | GTLGQGLSALQSEQG CCCHHHHHHHHHHHH | 33.48 | 22210691 | |
| 176 (in isoform 2) | Phosphorylation | - | 44.64 | 22210691 | |
| 177 | Phosphorylation | QGLSALQSEQGRLIQ HHHHHHHHHHHHHHH | 32.51 | - | |
| 178 (in isoform 2) | Phosphorylation | - | 44.06 | 22210691 | |
| 187 | Phosphorylation | GRLIQLLSESQGHMA HHHHHHHHHCCHHHH | 43.74 | 22210691 | |
| 265 | Phosphorylation | YSVFPTHYPAGFQVY EEECCCCCCCCEEEE | 9.39 | 22817900 | |
| 272 | Phosphorylation | YPAGFQVYCDMRTDG CCCCEEEEEEEECCC | 3.35 | 22817900 | |
| 340 | N-linked_Glycosylation | VDLEDFENGTAYARY CCHHHCCCCEEEEEE | 53.78 | UniProtKB CARBOHYD | |
| 378 | Phosphorylation | YSGTAGDSLLKHSGM CCCCCCCHHHHHCCC | 34.38 | 24719451 | |
| 446 | Phosphorylation | SWTGWQYSLKFSEMK CCCCCEEEEEEEECE | 15.24 | 24719451 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of FBCD1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of FBCD1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of FBCD1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of FBCD1_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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