FAS1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FAS1_ARATH
• UniProt AC: Q9SXY0
• Protein Name: Chromatin assembly factor 1 subunit FAS1
• Gene Name: FAS1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 815
• Subcellular Localization: Nucleus.
• Protein Description: Component of the chromatin assembly factor complex (CAF-1) involved in chromatin assembly following DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. Required for several aspects of development, including seedling growth and leaf hair differentiation. Plays a critical role in the organization of shoot apical meristem (SAM) and root apical meristem (RAM) during postembryonic development by facilitating stable maintenance of gene expression states. Seems not required to maintain transcriptional repression of heterochromatic genes. Involved in heterologous recombination. May repress endocycle..
• Protein Sequence: MDEVSTVNENENRKTMIEPKKLNKRKREPTAIENLTSEEKESQISSLNLEMKGLFDYFREVMDKSKRTDLFSGFSECSSLNSMVALLMEEMSLPLSKLVDEIYLKLKEKTESVTMVAVKSAVVSVGQRVSYGVLNVDADVLEDDSESCLWCWETRDLKIMPSSVRGVLKLRRTCRKKIHERITAVSAMLAALQREETEKLWRSDLSKAAEKLGKILSEVDIRSFMDNMMQKNSSEMAEKDSKREEKLLLKQLEKNRCEAEKEKKRMERQVLKEKLQQEKEQKLLQKAIVDENNKEKEETESRKRIKKQQDESEKEQKRREKEQAELKKQLQVQKQASIMERFLKKSKDSSLTQPKLPSSEVTAQELSCTKHENEIGKVVQAIDNAFSTTCEATVDDIRREHFASWRQLGHLLSSSKKHWGMRRQPKSELFPKLKLSTNSGVTSDGEPNMEKQGDGCEENNFDGRQCKPSSSNRKKSRRVKQLLQFDKSCRPGFYGIWPSQSQVVKPRRPLQKDPELDYEVDSDEEWEEEEAGESLSDCEKDEDESLEEGCSKADDEDDSEDDFMVPDGYLSEDEGVQVDRMDIDPSEQDANTTSSKQDQESPEFCALLQQQKHLQNLTDHALKKTQPLIICNLTHEKVSLLAAKDLEGTQKVEQICLRALMVRQFPWSSLIEISINDIQDEDQEASKFSCSQSTPPSNSKAKIIPDSDLLTVVSTIQSCSQGINRVVETLQQKFPDVPKTKLRQKVREISDFEDSRWQVKKEVLTKLGLSPSPDKGGKRLPKTISTFFSKRCLPPSTKPQPAVEDAAERLENENA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
299	Phosphorylation	NNKEKEETESRKRIK CHHHHHHHHHHHHHH		27643528
301	Phosphorylation	KEKEETESRKRIKKQ HHHHHHHHHHHHHHH		27643528
772	Phosphorylation	TKLGLSPSPDKGGKR HHCCCCCCCCCCCCC		25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FAS1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FAS1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FAS1_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of FAS1_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.