dbPTM

FACR3_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	FACR3_DROME
UniProt AC	Q960W6
Protein Name	Putative fatty acyl-CoA reductase CG8306 {ECO:0000250\|UniProtKB:Q8WVX9, ECO:0000312\|EMBL:AAF57977.2}
Gene Name	CG8306
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	516
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description	Catalyzes the reduction of C16 or C18 fatty acyl-CoA to fatty alcohols..
Protein Sequence	MASSPITDFYAGRNVFITGATGFVGVTIVEKLLRDVPNVGTLYLLMRAKKGKSVQERLEELKKNSVFDKFKELQLQSRLSKIVPIEGDVGLEHLGISPKDRQTLIDNVNVVFHSAATLDFFQSLKETTNINLRGTRRVVELCQQIKNLDALVHVSSAYVNAYLTKVEEKLYPAPEDPEKIIQLSETLNDDALKELEPKLLKDHPNTYTFTKHLAEHEVANVASKFPCGIVRPSMITAAWKEPIPGWTISKNGPQGFFMGASKGVLRRLPLDPSIIMDYIPIDVVVNGIITTGYYVNSLQAKNGGRPADLQIFHLTSSTYKPFRFELMTDKINSYLHDYPLNSAVWYPNLRLVKSLWVFRLSAILFHFIPAIILDLVTKIGGGRPILVRLHKNVWNSLNTLEKFIFTEWHFDSKRLLALSKTLNIVDKKKFFIDIGELAWDEYFSNTILGVRQYLSKEPIKNLEKARRKDKILLGLHVALQLSFWYGVFKLIVCLTGISTAKAALVLPVLYYLFGLL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
99	Ubiquitination	EHLGISPKDRQTLID HHCCCCHHHHCHHHH	59.77	31113955
456	Acetylation	GVRQYLSKEPIKNLE HHHHHHCCHHCCCHH	65.98	21791702

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of FACR3_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of FACR3_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of FACR3_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
KTAP2_DROME	CG31460	physical	22036573

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of FACR3_DROME

Related Literatures of Post-Translational Modification