FACR1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FACR1_MOUSE
• UniProt AC: Q922J9
• Protein Name: Fatty acyl-CoA reductase 1 {ECO:0000305|PubMed:15220348}
• Gene Name: Far1 {ECO:0000312|MGI:MGI:1914670}
• Organism: Mus musculus (Mouse).
• Sequence Length: 515
• Subcellular Localization: Peroxisome membrane ; Single-pass membrane protein .
• Protein Description: Catalyzes the reduction of saturated and unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols. [PubMed: 15220348]
• Protein Sequence: MVSIPEYYEGKNILLTGATGFLGKVLLEKLLRSCPRVNSVYVLVRQKAGQTPQERVEEILSSKLFDRLRDENPDFREKIIAINSELTQPKLALSEEDKEIIIDSTNVIFHCAATVRFNENLRDAVQLNVIATRQLILLAQQMKNLEVFMHVSTAYAYCNRKHIDEVVYPPPVDPKKLIDSLEWMDDGLVNDITPKLIGDRPNTYIYTKALAEYVVQQEGAKLNVAIVRPSIVGASWKEPFPGWIDNFNGPSGLFIAAGKGILRTMRASNNALADLVPVDVVVNTSLAAAWYSGVNRPRNIMVYNCTTGSTNPFHWGEVEYHVISTFKRNPLEQAFRRPNVNLTSNHLLYHYWIAVSHKAPAFLYDIYLRMTGRSPRMMKTITRLHKAMVFLEYFTSNSWVWNTDNVNMLMNQLNPEDKKTFNIDVRQLHWAEYIENYCMGTKKYVLNEEMSGLPAARKHLNKLRNIRYGFNTILVILIWRIFIARSQMARNIWYFVVSLCYKFLSYFRASSTMRY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MVSIPEYYEGKNIL -CCCCCCCCCCCCEE	11.06	28576409
90	Ubiquitination	NSELTQPKLALSEED CCCCCCCCCCCCHHH	36.25	22790023
90 (in isoform 4)	Ubiquitination	-	36.25	22790023
111	Glutathionylation	STNVIFHCAATVRFN CCCEEEEEEHHHCCC	1.60	24333276
371	Phosphorylation	YDIYLRMTGRSPRMM HHHHHHHHCCCHHHH	24.02	28059163
443	Ubiquitination	NYCMGTKKYVLNEEM HHHCCCCCHHHCHHH	40.19	22790023
443 (in isoform 4)	Ubiquitination	-	40.19	22790023
505 (in isoform 4)	Phosphorylation	-	25.92	21149613
506 (in isoform 4)	Phosphorylation	-	10.14	21149613
510 (in isoform 4)	Phosphorylation	-	23.29	21149613

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FACR1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FACR1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FACR1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of FACR1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.