FABPH_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FABPH_MOUSE
• UniProt AC: P11404
• Protein Name: Fatty acid-binding protein, heart
• Gene Name: Fabp3
• Organism: Mus musculus (Mouse).
• Sequence Length: 133
• Subcellular Localization: Cytoplasm.
• Protein Description: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters..
• Protein Sequence: MADAFVGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDTITIKTQSTFKNTEINFQLGIEFDEVTADDRKVKSLVTLDGGKLIHVQKWNGQETTLTRELVDGKLILTLTHGSVVSTRTYEKEA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MADAFVGTW ------CCCCCCEEE	19.48	-
8	Phosphorylation	MADAFVGTWKLVDSK CCCCCCEEEEECCCC	17.71	23737553
10	Acetylation	DAFVGTWKLVDSKNF CCCCEEEEECCCCCH	38.17	155519
15	Ubiquitination	TWKLVDSKNFDDYMK EEEECCCCCHHHHHH	58.11	22790023
20	Phosphorylation	DSKNFDDYMKSLGVG CCCCHHHHHHHCCCC	14.32	-
22	Ubiquitination	KNFDDYMKSLGVGFA CCHHHHHHHCCCCHH	35.98	22790023
23	Phosphorylation	NFDDYMKSLGVGFAT CHHHHHHHCCCCHHH	17.52	22817900
30	Phosphorylation	SLGVGFATRQVASMT HCCCCHHHHHHHCCC	21.26	22817900
38	Ubiquitination	RQVASMTKPTTIIEK HHHHCCCCCEEEEEE	31.55	22790023
45	Ubiquitination	KPTTIIEKNGDTITI CCEEEEEECCCEEEE	56.68	22790023
53	Ubiquitination	NGDTITIKTQSTFKN CCCEEEEEECCEECC	31.68	22790023
82	Ubiquitination	TADDRKVKSLVTLDG CCCCCEEEEEEEEEC	40.90	22790023
83	Phosphorylation	ADDRKVKSLVTLDGG CCCCEEEEEEEEECC	30.93	-
91	Ubiquitination	LVTLDGGKLIHVQKW EEEEECCEEEEEEEE	50.20	22790023
97	Ubiquitination	GKLIHVQKWNGQETT CEEEEEEEECCCEEE	41.35	22790023
122	Phosphorylation	ILTLTHGSVVSTRTY EEEEECCCEEEEEEE	16.25	23737553
125	Phosphorylation	LTHGSVVSTRTYEKE EECCCEEEEEEEECC	15.26	23737553
126	Phosphorylation	THGSVVSTRTYEKEA ECCCEEEEEEEECCC	18.54	23737553

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
20	Y	Phosphorylation	Kinase	TYR-KINASES	-	Uniprot

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FABPH_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FABPH_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of FABPH_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.