FABP5_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: FABP5_MOUSE
• UniProt AC: Q05816
• Protein Name: Fatty acid-binding protein 5 {ECO:0000305}
• Gene Name: Fabp5
• Organism: Mus musculus (Mouse).
• Sequence Length: 135
• Subcellular Localization: Cytoplasm . Nucleus . Cell junction, synapse . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Secreted . Localizes primarily to the cytoplasm. Upon certain ligand binding, a conformation change exposes a nuclear localizati
• Protein Description: Intracellular carrier for long-chain fatty acids and related active lipids, such as the endocannabinoid, that regulates the metabolism and actions of the ligands they bind. [PubMed: 8608126]
• Protein Sequence: MASLKDLEGKWRLMESHGFEEYMKELGVGLALRKMAAMAKPDCIITCDGNNITVKTESTVKTTVFSCNLGEKFDETTADGRKTETVCTFQDGALVQHQQWDGKESTITRKLKDGKMIVECVMNNATCTRVYEKVQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MASLKDLEG ------CCCHHHHCH	24.46	-
3	Phosphorylation	-----MASLKDLEGK -----CCCHHHHCHH	34.35	27742792
5	Acetylation	---MASLKDLEGKWR ---CCCHHHHCHHHH	58.74	23954790
5	Succinylation	---MASLKDLEGKWR ---CCCHHHHCHHHH	58.74	23954790
16	Phosphorylation	GKWRLMESHGFEEYM HHHHHHHHCCHHHHH	18.23	28638064
24	Ubiquitination	HGFEEYMKELGVGLA CCHHHHHHHHCHHHH	49.22	22790023
34	Ubiquitination	GVGLALRKMAAMAKP CHHHHHHHHHHHCCC	33.47	22790023
40	Acetylation	RKMAAMAKPDCIITC HHHHHHCCCCEEEEE	28.44	22826441
43	S-nitrosocysteine	AAMAKPDCIITCDGN HHHCCCCEEEEECCC	3.08	-
43	S-palmitoylation	AAMAKPDCIITCDGN HHHCCCCEEEEECCC	3.08	28680068
43	S-nitrosylation	AAMAKPDCIITCDGN HHHCCCCEEEEECCC	3.08	22178444
43	Glutathionylation	AAMAKPDCIITCDGN HHHCCCCEEEEECCC	3.08	24333276
47	Glutathionylation	KPDCIITCDGNNITV CCCEEEEECCCCEEE	4.43	24333276
55	Acetylation	DGNNITVKTESTVKT CCCCEEEEECCEEEE	37.61	22826441
61	Acetylation	VKTESTVKTTVFSCN EEECCEEEEEEEECC	38.27	22826441
61	Ubiquitination	VKTESTVKTTVFSCN EEECCEEEEEEEECC	38.27	22790023
66	Phosphorylation	TVKTTVFSCNLGEKF EEEEEEEECCCCCCC	9.58	29514104
67	S-palmitoylation	VKTTVFSCNLGEKFD EEEEEEECCCCCCCC	3.11	28526873
72	Ubiquitination	FSCNLGEKFDETTAD EECCCCCCCCEECCC	57.21	-
72	Acetylation	FSCNLGEKFDETTAD EECCCCCCCCEECCC	57.21	22826441
82	Succinylation	ETTADGRKTETVCTF EECCCCCEEEEEEEE	57.13	23806337
82	Acetylation	ETTADGRKTETVCTF EECCCCCEEEEEEEE	57.13	23806337
87	S-nitrosocysteine	GRKTETVCTFQDGAL CCEEEEEEEECCCCE	4.05	-
87	S-nitrosylation	GRKTETVCTFQDGAL CCEEEEEEEECCCCE	4.05	21278135
103	Acetylation	QHQQWDGKESTITRK EEEECCCCCCEEEEE	46.12	22826441
120	S-nitrosocysteine	DGKMIVECVMNNATC CCCEEEEEECCCCEE	2.14	-
120	Glutathionylation	DGKMIVECVMNNATC CCCEEEEEECCCCEE	2.14	24333276
120	S-nitrosylation	DGKMIVECVMNNATC CCCEEEEEECCCCEE	2.14	22178444
120	S-palmitoylation	DGKMIVECVMNNATC CCCEEEEEECCCCEE	2.14	28526873
127	S-nitrosocysteine	CVMNNATCTRVYEKV EECCCCEEEEEEHHC	1.81	-
127	Glutathionylation	CVMNNATCTRVYEKV EECCCCEEEEEEHHC	1.81	24333276
127	S-nitrosylation	CVMNNATCTRVYEKV EECCCCEEEEEEHHC	1.81	22178444
127	S-palmitoylation	CVMNNATCTRVYEKV EECCCCEEEEEEHHC	1.81	28526873
131	Phosphorylation	NATCTRVYEKVQ--- CCEEEEEEHHCC---	13.52	25367039

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of FABP5_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of FABP5_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of FABP5_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of FABP5_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.